SCHEMBL45023

SCHEMBL45023

CC(Cl)Cc1cccc(CC(C)Cl)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 2/20 0.52
TAAR1 Q96RJ0 6/20 0.44
SLC6A2 P23975 3/20 0.44
SIGMAR1 Q99720 3/20 0.44
SLC6A4 P31645 2/20 0.44
SLC6A3 Q01959 2/20 0.44
MAOA P21397 1/20 0.44
CYP2A6 P11509 1/20 0.44
ADORA2A P29274 1/20 0.44
ADORA1 P30542 1/20 0.44
HTR2A P28223 3/20 0.42
HTR2B P41595 3/20 0.42
HTR2C P28335 2/20 0.42
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
ADRA2C P18825 1/20 0.37
ADRA1A P35348 1/20 0.37
DRD3 P35462 1/20 0.37
OPRK1 P41145 1/20 0.37
SLC18A2 Q05940 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28287500 0.85 PNMT (0.48) PNMTTAAR1SLC6A2SIGMAR1SLC6A4
SCHEMBL45291 0.84 PNMT (0.33) PNMTSLC6A2SLC6A3HTR2AHTR2B
SCHEMBL66064 0.82 SIGMAR1 (0.58) TAAR1SLC6A2SIGMAR1SLC6A4SLC6A3
SCHEMBL27878590 0.82 SIGMAR1 (0.58) TAAR1SLC6A2SIGMAR1SLC6A4SLC6A3
SCHEMBL4445053 0.82 HTR2A (0.50) PNMTTAAR1SIGMAR1SLC6A4HTR2A
Ammonia Solution, Strong SCHEMBL8142874 0.80 SIGMAR1 (0.56) TAAR1SLC6A2SIGMAR1SLC6A4SLC6A3
Hydrochloric Acid SCHEMBL22207848 0.80 SIGMAR1 (0.56) TAAR1SLC6A2SIGMAR1SLC6A4SLC6A3
SCHEMBL8539519 0.79 GABRA1 (0.50) PNMTTAAR1SLC6A2SIGMAR1SLC6A4
SCHEMBL8680649 0.79 SLC7A5 (0.40) PNMTTAAR1
SCHEMBL45200 0.78 SLC6A2 (0.48) TAAR1SLC6A2SIGMAR1SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118955941-A PEDOT dispersion and preparation method and application thereof 东莞东阳光科研发有限公司 2024-11-15 CN claimed
US-8063154-B2 Preparation of exo-olefin terminated polyolefins via quenching with alkoxysilanes or ethers THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2011-11-22 US claimed
US-8013073-B2 Method for preparing polyolefins containing vinylidine end groups using nonaromatic heterocyclic compounds CHEVRON ORONITE COMPANY LLC (US) 2011-09-06 US claimed
EP-2279214-A1 PRODUCTION OF VINYLIDENE-TERMINATED POLYOLEFINS VIA QUENCHING WITH MONOSULFIDES Chevron Oronite Company LLC (US) 2011-02-02 EP claimed
US-7816459-B2 Method for preparing polyolefins containing vinylidine end groups using polymeric nitrogen compounds CHEVRON ORONITE COMPANY LLC (US) 2010-10-19 US claimed
EP-1803751-B1 Method for preparing polyolefins containing vinylidene end groups using polymeric nitrogen compounds CHEVRON ORONITE CO (US) 2010-06-30 EP claimed
EP-1803748-B1 Method for preparing polyolefins containing vinylidene end groups using nonaromatic heterocyclic compounds CHEVRON ORONITE CO (US) 2010-06-09 EP claimed
US-20090318624-A1 Preparation of exo-olefin terminated polyolefins via quenching with alkoxysilanes or ethers UNIVERSITY OF SOUTHERN MISSISSIPPI 2009-12-24 US claimed
US-20090247716-A1 Production of Vinylidene-Terminated Polyolefins Via Quenching with Monosulfides CHEVRON ORONITE COMPANY LLC 2009-10-01 US claimed
WO-2009120551-A1 PRODUCTION OF VINYLIDENE-TERMINATED POLYOLEFINS VIA QUENCHING WITH MONOSULFIDES CHEVRON ORONITE COMPANY LLC (US) 2009-10-01 WO claimed
US-7501476-B2 contacting a olefin monomer (isobutylene) with an initiator( 2-chloro-2,4,4,-trimethylpentane) in the presence of a Lewis acid and solvent under suitable quasiliving polymerization reaction conditions, contacting quasiliving carbocationically terminated polymer with an oxazole or thiazoles quencher CHEVRON ORONITE COMPANY, LLC (US) 2009-03-10 US claimed
EP-1803741-B1 Method for preparing polyolefins containing vinylidene groups using azole compounds CHEVRON ORONITE CO (US) 2009-01-21 EP claimed
US-20070155911-A1 Method for preparing polyolefins containing vinylidine end groups using nonaromatic heterocyclic compounds UNIVERSITY OF SOUTHERN MISSISSIPPI 2007-07-05 US claimed
US-20070155910-A1 Method for preparing polyolefins containing vinylidine end groups using polymeric nitrogen compounds CHEVRON ORONITE COMPANY LLC 2007-07-05 US claimed
US-20070155908-A1 contacting a olefin monomer (isobutylene) with an initiator( 2-chloro-2,4,4,-trimethylpentane) in the presence of a Lewis acid and solvent under suitable quasiliving polymerization reaction conditions, contacting quasiliving carbocationically terminated polymer with an oxazole or thiazoles quencher CHEVRON ORONITE COMPANY LLC 2007-07-05 US claimed
EP-1803748-A1 Method for preparing polyolefins containing vinylidene end groups using nonaromatic heterocyclic compounds Chevron Oronite Company LLC (US) 2007-07-04 EP claimed
EP-1803751-A1 Method for preparing polyolefins containing vinylidene end groups using polymeric nitrogen compounds Chevron Oronite Company LLC (US) 2007-07-04 EP claimed
EP-1803741-A1 Method for preparing polyolefins containing vinylidene groups using azole compounds Chevron Oronite Company LLC (US) 2007-07-04 EP claimed
EP-4508101-B1 PROCESS FOR MANUFACTURING OF POLYISOBUTENE SUCCINIC ANHYDRIDES BASF SE (DE) 2026-03-25 EP disclosed
EP-0164521-A1 Process for the preparation of polymeric tertiary aralkyl isocyanates from 1,3- or 1,4-bis(1-chloro-1-methylethyl)benzene AMERICAN CYANAMID COMPANY (US) 1985-12-18 EP disclosed