Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 9/20 | 0.34 |
| ▸ | CA2 | P00918 | 9/20 | 0.34 |
| ▸ | CA9 | Q16790 | 8/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 3/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.33 |
| ▸ | CA3 | P07451 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA6 | P23280 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13536933 | 0.98 | TSHR (0.43) | TSHRALDH1A1CA1CA2CA9 | |
| SCHEMBL9492380 | 0.90 | TSHR (0.35) | TSHRALDH1A1HCAR2 | |
| SCHEMBL7164576 | 0.78 | — | — | |
| SCHEMBL1928774 | 0.76 | TSHR (0.34) | TSHRALDH1A1CA1CA2CA9 | |
| SCHEMBL27267694 | 0.76 | TSHR (0.43) | TSHRALDH1A1 | |
| SCHEMBL4765473 | 0.76 | TSHR (0.41) | TSHRALDH1A1HCAR2HPGD | |
| SCHEMBL27998806 | 0.74 | ALDH1A1 (0.31) | TSHRALDH1A1 | |
| SCHEMBL8574590 | 0.74 | THRB (0.37) | TSHRALDH1A1CA1CA2CA9 | |
| SCHEMBL11111063 | 0.74 | HCAR2 (0.42) | TSHRALDH1A1HCAR2HPGD | |
| SCHEMBL1347487 | 0.74 | HCAR2 (0.42) | TSHRALDH1A1HCAR2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707559-A | PROVIDING A STABLE 1,2-DIOXETANE WHICH FORMS INTERMEDIATE UNSTABLE COMPOUNDS WHEN TRIGGERED TO REMOVE BLOCKING GROUPS BY ACTIVATING AGENT SO THAT UNSTABLE COMPOUND DECOMPOSES TO FORM LIGHT AND TWO CARBONYL COMPOUNDS | TROPIX, INC. (US) | 1998-01-13 | — | — | US | claimed |
| US-5004565-A | Method and compositions providing enhanced chemiluminescence from 1,2-dioxetanes | THE BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) | 1991-04-02 | — | — | US | claimed |
| US-4959182-A | Method and compositions providing enhanced chemiluminescence from 1,2-dioxetanes | BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) | 1990-09-25 | — | — | US | claimed |
| EP-0352713-A1 | Method and compositions providing enhanced chemiluminescence from 1,2-dioxetanes | TROPIX, INC. (US) | 1990-01-31 | — | — | EP | claimed |
| EP-0254051-A2 | Chemiluminescent 1,2-dioxetane compounds | THE BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) | 1988-01-27 | — | — | EP | claimed |
| EP-0069622-B1 | PROCESS FOR THE PREPARATION OF BETA-CYCLO-SUBSTITUTED ETHYL AMINES, AND PRODUCTS SO OBTAINED | SANOFI S.A. (FR) | 1985-09-18 | — | — | EP | claimed |