Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11105630 | 0.87 | HCAR2 (0.37) | HCAR2TSHRHPGDALDH1A1ATM | |
| SCHEMBL1347487 | 0.86 | HCAR2 (0.42) | HCAR2TSHRCES2HPGDPLA2G2C | |
| SCHEMBL27976697 | 0.85 | ZDHHC20 (0.43) | HCAR2TSHRCES2HPGDPLA2G2C | |
| SCHEMBL11110109 | 0.80 | ALDH1A1 (0.38) | HCAR2TSHRALDH1A1 | |
| SCHEMBL17466647 | 0.79 | TSHR (0.42) | HCAR2TSHRHPGDALDH1A1ATM | |
| SCHEMBL11111060 | 0.78 | TSHR (0.44) | HCAR2TSHRCES2HPGDALDH1A1 | |
| SCHEMBL11036842 | 0.76 | MAPT (0.35) | TSHRALDH1A1 | |
| SCHEMBL11884618 | 0.74 | HCAR2 (0.47) | HCAR2TSHRHPGDALDH1A1ATM | |
| SCHEMBL27907040 | 0.74 | ZDHHC20 (0.44) | HCAR2TSHRCES2HPGDPLA2G2C | |
| SCHEMBL8680666 | 0.74 | TSHR (0.39) | HCAR2TSHRHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103895-A2 | Novel hydroxylamine derivatives, production and use thereof | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1984-03-28 | — | — | EP | disclosed |