Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10633563 | 0.91 | SLC6A2 (0.54) | AOC3GRIN1GRIN2BGMNNTP53 | |
| SCHEMBL13391312 | 0.88 | SLC6A2 (0.46) | AOC3GRIN1GRIN2BGMNNTP53 | |
| Hydrochloric Acid SCHEMBL15535999 | 0.86 | SLC6A2 (0.48) | GRIN1GRIN2BGMNNTP53CYP3A4 | |
| SCHEMBL15535932 | 0.81 | TP53 (0.44) | GRIN1GRIN2BGMNNTP53CYP3A4 | |
| SCHEMBL23536506 | 0.80 | SLC18A3 (0.45) | — | |
| SCHEMBL17609122 | 0.80 | SLC18A3 (0.45) | — | |
| SCHEMBL13308375 | 0.79 | SLC18A3 (0.47) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16622109 | 0.79 | CYP1A2 (0.58) | AOC3 | |
| SCHEMBL16622110 | 0.79 | CYP1A2 (0.58) | AOC3 | |
| SCHEMBL13741859 | 0.79 | CYP1A2 (0.58) | AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106883266-B | Preparation method of 1- (4-chlorphenyl) -2-cyclopropyl-1-acetone and intermediate thereof | 江苏七洲绿色化工股份有限公司 | 2020-03-17 | — | — | CN | disclosed |
| CN-103044230-B | Preparation method of 1-(4-chlorphenyl)-2-cyclopropyl-1-acetone | HUNAN CHEMICAL ENGINEERING INST. (CN) | 2014-10-08 | — | — | CN | disclosed |
| CN-102584558-B | Preparation method of 1-(4-chlorphenyl)-2-cyclopropyl-1-acetone | HUNAN RES INST CHEMICAL IND | 2013-10-30 | — | — | CN | disclosed |
| CN-103044230-A | Preparation method of 1-(4-chlorphenyl)-2-cyclopropyl-1-acetone | HUNAN RES INST CHEMICAL IND | 2013-04-17 | — | — | CN | disclosed |
| CN-102584558-A | Preparation method of 1-(4-chlorphenyl)-2-cyclopropyl-1-acetone | HUNAN RES INST CHEMICAL IND | 2012-07-18 | — | — | CN | disclosed |
| EP-2440535-A1 | ANTIFUNGAL 1,2,4-TRIAZOLYL DERIVATIVES HAVING A 5- SULFUR SUBSTITUENT | BASF SE (DE) | 2012-04-18 | — | — | EP | disclosed |
| US-20120077676-A1 | Antifungal 1,2,4-Triazolyl Derivatives Having a 5-Sulfur Substituent | BASF SE (DE) | 2012-03-29 | — | — | US | disclosed |
| WO-2010142779-A1 | ANTIFUNGAL 1,2,4-TRIAZOLYL DERIVATIVES HAVING A 5- SULFUR SUBSTITUENT | BASF SE (DE) | 2010-12-16 | — | — | WO | disclosed |
| EP-0900218-B1 | HETEROCYCLIC COMPOUNDS | LILLY CO ELI (US) | 2002-07-24 | — | — | EP | disclosed |
| EP-0900218-A4 | HETEROCYCLIC COMPOUNDS | LILLY CO ELI (US) | 2001-05-23 | — | — | EP | disclosed |
| US-6117883-A | Heterocyclic compounds | ELI LILLY AND COMPANY (US) | 2000-09-12 | — | — | US | disclosed |
| EP-0900218-A1 | HETEROCYCLIC COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-03-10 | — | — | EP | disclosed |
| CN-1041717-C | Cyclopropane derivatives | SANDOZ LTD (CH) | 1999-01-20 | — | — | CN | disclosed |
| US-5770741-A | FUNGICIDE INTERMEDIATE | SANDOZ LTD. (CH) | 1998-06-23 | — | — | US | disclosed |
| WO-1997040044-A1 | HETEROCYCLIC COMPOUNDS | ELI LILLY AND COMPANY (US) | 1997-10-30 | — | — | WO | disclosed |
| EP-0321409-B1 | CYCLOPROPANE DERIVATIVES | SANDOZ AG (CH) | 1993-03-17 | — | — | EP | disclosed |
| US-4973767-A | SUBSTITUTED ETHANOLS, CHEMICAL INTERMEDIATES FOR FUNGICIDES | SANDOZ LTD. (CH) | 1990-11-27 | — | — | US | disclosed |
| CN-1035494-A | The preparation method of cyclopropane derivative | SANDOZ LTD (CH) | 1989-09-13 | — | — | CN | disclosed |
| EP-0321409-A2 | Cyclopropane derivatives | SANDOZ AG (CH) | 1989-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077676-A1 | Antifungal 1,2,4-Triazolyl Derivatives Having a 5-Sulfur Substituent | ERG28, STS, CYP51A1 | AOC3 357/4885GRIN1 1668/4885GRIN2B 2208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.