Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 5/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7868811 | 0.85 | GABRA1 (0.43) | GABRA1GABRB1LMNAGABRB2CA1 | |
| SCHEMBL28576004 | 0.81 | GABRA1 (0.43) | GABRA1GABRB1LMNAGABRB2CA1 | |
| SCHEMBL13862920 | 0.75 | PRKCI (0.52) | GABRA1GABRB2PRKCIELANECTSG | |
| SCHEMBL7066182 | 0.74 | GABRA1 (0.59) | GABRA1GABRB1LMNAGABRB2CA1 | |
| SCHEMBL31028132 | 0.74 | GABRA1 (0.59) | GABRA1GABRB1LMNAGABRB2CA1 | |
| SCHEMBL15994580 | 0.72 | PRKCI (0.44) | HTR2BCYP3A4TSHRPRKCICHRM1 | |
| SCHEMBL16736888 | 0.71 | LMNA (0.55) | GABRA1GABRB1LMNASLC6A2HTR2B | |
| SCHEMBL159123 | 0.71 | GABRA1 (0.48) | GABRA1GABRB1LMNAGABRB2CA1 | |
| SCHEMBL22845074 | 0.71 | GABRA1 (0.48) | GABRA1GABRB1LMNAGABRB2CA1 | |
| SCHEMBL9114093 | 0.71 | PRKCI (0.47) | LMNACYP3A4HPGDTSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716443-A | MIXTURES OF POLYDIMETHYLSILOXANE, ANOTHER POLYSILOXANE HAVING MONOMERS CONTAINING AMINOALKYL GROUPS, ORGANIC ACIDS AND AQUEOUS ORGANIC SOLVENTS | TAIHO INDUSTRIES, CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| US-5584917-A | POLYSILOXANE WITH TERT-AMINO GROUP; DURABILITY, ONE STEP TREATMENT | TAIHO INDUSTRIES CO., LTD. (JP) | 1996-12-17 | — | — | US | disclosed |