Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 5/20 | 0.59 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.59 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.59 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | FAAH | O00519 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.59 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31028132 | 1.00 | GABRA1 (0.59) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL2672714 | 0.89 | GABRA1 (0.55) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL4316141 | 0.87 | ALOX5 (0.57) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL11656789 | 0.86 | ALOX5 (0.55) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL6870041 | 0.85 | TSHR (0.53) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL9161857 | 0.85 | GABRA1 (0.43) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL4459158 | 0.84 | GABRA1 (0.64) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL14310641 | 0.83 | GABRA1 (0.57) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL4310555 | 0.83 | GABRA1 (0.57) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL21734367 | 0.82 | GABRA1 (0.67) | GABRA1GABRB2GABRG2GABRB3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114133318-B | Method for reducing and removing propofol impurity O in propofol product | 广东嘉博制药有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-114133318-A | Method for reducing and removing propofol impurity O in propofol product | 广东嘉博制药有限公司 | 2022-03-04 | — | — | CN | claimed |
| EP-3845225-B1 | GABAA RECEPTOR ALLOSTERIC ENHANCER FOR USE IN THE TREATMENT OF EPILEPSY | XIAN LIBANG ZHAOXIN BIOTECHNOLOGY CO LTD (CN) | 2025-02-12 | — | — | EP | disclosed |
| CN-220989713-U | Crystallization desolventizing rectifying device for liquid compound | 威海市文登区检验检测中心 | 2024-05-24 | — | — | CN | disclosed |
| CN-117298637-A | Crystallization desolventizing rectifying device for liquid compound and control method thereof | 威海市文登区检验检测中心 | 2023-12-29 | — | — | CN | disclosed |
| CN-114133318-B | Method for reducing and removing propofol impurity O in propofol product | 广东嘉博制药有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-114133318-B | Method for reducing and removing propofol impurity O in propofol product | 广东嘉博制药有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-114133318-B | Method for reducing and removing propofol impurity O in propofol product | 广东嘉博制药有限公司 | 2023-08-29 | — | — | CN | disclosed |
| US-11684591-B2 | Use of a GABAA receptor allosteric enhancer in medicine | XI'AN LIBANG ZHAOXIN BIOTECHNOLOGY CO., LTD (CN) | 2023-06-27 | — | — | US | disclosed |
| CN-110870856-B | GABA (Gamma-aminobutyric acid) A Application of receptor allosteric enhancer in medicine | 西安力邦肇新生物科技有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-114133318-A | Method for reducing and removing propofol impurity O in propofol product | 广东嘉博制药有限公司 | 2022-03-04 | — | — | CN | disclosed |
| US-10329243-B2 | Biphenyl derivative and uses thereof | XI'AN LIBANG PHARMACEUTICAL CO., LTD (CN) | 2019-06-25 | — | — | US | disclosed |
| US-20180141895-A1 | DIPHENYL DERIVATIVE AND USES THEREOF | XI'AN LIBANG PHARMACEUTICAL CO., LTD (CN) | 2018-05-24 | — | — | US | disclosed |
| EP-3246304-A2 | DIPHENYL DERIVATIVE AND USES THEREOF | Xi'an Libang Pharmaceutical Co., Ltd (CN) | 2017-11-22 | — | — | EP | disclosed |
| US-20140031435-A1 | PROPOFOL COMPOSITIONS AND METHODS FOR REDUCING PAIN ASSOCIATED WITH PROPOFOL INJECTION | ZHANG RENSHENG VICTOR (US) | 2014-01-30 | — | — | US | disclosed |
| CN-100569720-C | The production method of refining propofol by dynamic accumulative distillation | XI AN LIBANG PHARMACEUTICAL CO (CN) | 2009-12-16 | — | — | CN | disclosed |
| CN-101139258-A | Production method for refining propofol by dynamic accumulative distillation | XIAN LIBANG PHARMACEUTICAL CO (CN) | 2008-03-12 | — | — | CN | disclosed |
| EP-0995737-B1 | Process for producing 3,3,5-trimethylcyclohexylidenebisphenols | HONSHU CHEMICAL IND (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6284931-B1 | REACTION OF 3,3,5-TRIMETHYLCYCLOHEXANONE AND PHENOL TO FORM DIPHENOL DERIVATIVE | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-09-04 | — | — | US | disclosed |
| EP-0995737-A1 | Process for producing 3,3,5-trimethylcyclohexylidenebisphenols | Honshu Chemical Industry Co. Ltd. (JP) | 2000-04-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031435-A1 | PROPOFOL COMPOSITIONS AND METHODS FOR REDUCING PAIN ASSOCIATED WITH PROPOFOL INJECTION | OPRL1, P2RX5, P2RY6 | GABRA1 250/4885GABRB2 371/4885GABRG2 322/4885 |
| US-11684591-B2 | Use of a GABAA receptor allosteric enhancer in medicine | GABRE, GABRB2, GABRB1 | GABRA1 7/4885GABRB2 2/4885GABRG2 12/4885 |
| US-10329243-B2 | Biphenyl derivative and uses thereof | PPARD, PCSK9, UGT2B7 | GABRA1 140/4885GABRB2 50/4885GABRG2 219/4885 |
| US-20180141895-A1 | DIPHENYL DERIVATIVE AND USES THEREOF | PPARD, DPP3, DPP7 | GABRA1 547/4885GABRB2 408/4885GABRG2 970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.