Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.56 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.56 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.56 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.56 |
| ▸ | CHRNA7 | P36544 | 10/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5520683 | 0.86 | DRD2 (0.59) | GAADRD2HTR2AHTR2BALDH1A1 | |
| SCHEMBL1439894 | 0.86 | TYK2 (0.52) | GAAPDK1PDK2PDK3PDK4 | |
| SCHEMBL11402399 | 0.85 | PDK1 (0.59) | GAAPDK1PDK2PDK3PDK4 | |
| SCHEMBL4099006 | 0.84 | GAA (0.51) | GAAPDK1PDK2PDK3PDK4 | |
| SCHEMBL2921682 | 0.83 | PDK1 (0.58) | GAAPDK1PDK2PDK3PDK4 | |
| SCHEMBL9037897 | 0.82 | GAA (0.66) | GAAPDK1PDK2PDK3PDK4 | |
| SCHEMBL11735899 | 0.81 | PDK1 (0.56) | GAAPDK1PDK2PDK3PDK4 | |
| Hydrochloric Acid SCHEMBL9004815 | 0.81 | GAA (0.64) | GAAPDK1PDK2PDK3PDK4 | |
| SCHEMBL7168272 | 0.80 | DRD2 (0.55) | GAAPDK1PDK2PDK3PDK4 | |
| SCHEMBL14889779 | 0.79 | POLB (0.56) | GAADRD2HTR2AHTR2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867525-A | Dihydrocyclopentaisoquinoline derivatives | UCB生物制药有限责任公司 | 2022-08-05 | — | — | CN | claimed |
| CN-114867525-A | Dihydrocyclopentaisoquinoline derivatives | UCB生物制药有限责任公司 | 2022-08-05 | — | — | CN | disclosed |
| US-5780483-A | IL-8 receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1998-07-14 | — | — | US | disclosed |
| EP-0182166-B1 | PROCESS FOR PREPARING PHENYLISOPROPYLUREA COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1989-05-31 | — | — | EP | disclosed |
| US-4578513-A | Process for preparing phenylisopropylurea compounds | AMERICAN CYANAMID COMPANY (US) | 1986-03-25 | — | — | US | disclosed |