SCHEMBL86823

SCHEMBL86823

C=CC(=O)N1CCC(=O)c2cc(Cl)ccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.44
LMNA P02545 1/20 0.44
NOTUM Q6P988 2/20 0.43
NPC1 O15118 1/20 0.40
MAPT P10636 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ACHE P22303 2/20 0.40
TET3 O43151 1/20 0.39
KMT2A Q03164 1/20 0.39
FBXL19 Q6PCT2 1/20 0.39
CXXC5 Q7LFL8 1/20 0.39
KDM2B Q8NHM5 1/20 0.39
CXXC4 Q9H2H0 1/20 0.39
KDM2A Q9Y2K7 1/20 0.39
PAX8 Q06710 1/20 0.37
VHL P40337 1/20 0.37
ELOC Q15369 1/20 0.37
ELOB Q15370 1/20 0.37
CCNK O75909 1/20 0.37
CDK12 Q9NYV4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11141196 0.82 NOTUM (0.48) RAB9ALMNANOTUMKMT2AVHL
SCHEMBL11147651 0.81 NOTUM (0.66) NOTUMMAPTHSD17B3
SCHEMBL31562020 0.80 LMNA (0.66) RAB9ALMNANOTUMNPC1MAPT
SCHEMBL11147595 0.78 NOTUM (0.47) NOTUMMAPTKMT2AVHLELOC
SCHEMBL9537963 0.78 MAPT (0.48) RAB9ALMNANOTUMMAPTSMN1; SMN2
SCHEMBL9535907 0.78 NOTUM (0.47) NOTUMMAPTHTT
SCHEMBL11069145 0.78 NOTUM (0.47) LMNANOTUMMAPTKMT2ASRD5A1
SCHEMBL9803723 0.77 AVPR2 (0.51) NOTUMSMN1; SMN2
SCHEMBL18533257 0.76 HDAC1 (0.56) RAB9ALMNANOTUMNPC1MAPT
SCHEMBL26916403 0.75 NOTUM (0.44) NOTUMKMT2ASRD5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2053095-B1 Ink composition and inkjet recording method using the same FUJIFILM CORP (JP) 2014-03-26 EP disclosed
US-8129447-B2 Ink composition and inkjet recording method using the same FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8129447-B2 Ink composition and inkjet recording method using the same FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
EP-2053095-A2 Ink composition and inkjet recording method using the same Fujifilm Corporation (JP) 2009-04-29 EP disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME RB1, IK, NOX1 RAB9A 974/4885LMNA 3581/4885NOTUM 3865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.