Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9393233 | 0.84 | NPSR1 (0.48) | OPRD1BCHEMEN1KMT2A | |
| SCHEMBL8551932 | 0.78 | BCHE (0.55) | ALDH1A1KDM4EMAPTHPGDBCHE | |
| Hydrochloric Acid SCHEMBL8555538 | 0.77 | MEN1 (0.54) | ALDH1A1KDM4EMAPTHPGDBCHE | |
| SCHEMBL29014297 | 0.76 | OPRD1 (0.48) | OPRD1 | |
| SCHEMBL26135660 | 0.74 | SCN1A (0.49) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL18832119 | 0.72 | BCHE (0.46) | OPRD1BCHE | |
| SCHEMBL11038501 | 0.72 | SCN1A (0.46) | OPRD1MEN1KMT2ASCN1ASCN2A | |
| SCHEMBL599342 | 0.70 | SMN1; SMN2 (0.56) | ALDH1A1MAPTHPGDSCN1ASCN2A | |
| SCHEMBL2771500 | 0.70 | GBA1 (0.50) | OPRD1BCHEMEN1KMT2A | |
| SCHEMBL30339801 | 0.70 | OPRD1 (0.44) | OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753679-A | SCIZOPHRENIA | HOFFMANN-LA ROCHE INC. (US) | 1998-05-19 | — | — | US | claimed |