Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8683051 | 0.84 | ALDH1A1 (0.51) | MEN1KMT2ABCHEOPRD1 | |
| SCHEMBL26135660 | 0.81 | SCN1A (0.49) | MEN1KMT2ACHRNA7CHRNB2CHRNA5 | |
| SCHEMBL18832119 | 0.80 | BCHE (0.46) | NPSR1BCHEMAOBOPRD1 | |
| SCHEMBL29014297 | 0.80 | OPRD1 (0.48) | SPHK1OPRD1 | |
| SCHEMBL2771500 | 0.78 | GBA1 (0.50) | MEN1KMT2ABCHEMAOBOPRD1 | |
| SCHEMBL11038501 | 0.77 | SCN1A (0.46) | MEN1KMT2ACHRNA7CHRNB2CHRNA5 | |
| SCHEMBL30724547 | 0.76 | SIGMAR1 (0.49) | — | |
| SCHEMBL7508265 | 0.75 | ALDH1A1 (0.44) | SPHK1 | |
| SCHEMBL6659539 | 0.75 | ALDH1A1 (0.44) | SPHK1 | |
| SCHEMBL765918 | 0.75 | CARM1 (0.57) | MEN1KMT2ABCHEMAOBCHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994020062-A2 | BALANOIDS AS PROTEIN KINASE C INHIBITORS | ELI LILLY AND COMPANY (US) | 1994-09-15 | — | — | WO | disclosed |