Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.40 |
| ▸ | ITGAV | P06756 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4958032 | 0.90 | CSNK2A2 (0.43) | ITGB3ITGAVITGB5HTTTP53 | |
| SCHEMBL8683774 | 0.86 | SLC16A3 (0.41) | ITGB3ITGAVITGB5RAB9AGAA | |
| SCHEMBL28472884 | 0.76 | TLR8 (0.41) | SMN1; SMN2NPC1HTTALDH1A1HPGD | |
| SCHEMBL7980652 | 0.75 | ITGB3 (0.61) | ITGB3ITGAVITGA2B | |
| SCHEMBL7658563 | 0.75 | ALDH1A1 (0.43) | SMN1; SMN2NPC1RAB9AHTTTP53 | |
| SCHEMBL7982200 | 0.75 | ITGAV (0.61) | ITGB3ITGAVITGB1ITGA2B | |
| SCHEMBL27272748 | 0.75 | SLC22A12 (0.44) | SMN1; SMN2NPC1HTTALDH1A1HPGD | |
| SCHEMBL28468125 | 0.75 | LOXL2 (0.46) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL7656202 | 0.74 | KDM4E (0.38) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL7979100 | 0.74 | ITGAV (0.68) | ITGB3ITGAVITGB1ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760028-A | TREATING CANCER METASTASIS, DIABETIC RETINOPATHY, NEOVASCULAR GLAUCOMA, THROMBOSIS, RESTENOSIS, OSTEOPOROSIS, MACULAR DEGENERATION | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-06-02 | — | — | US | disclosed |