Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.80 |
| ▸ | MAPT | P10636 | 4/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177294 | 0.92 | MAPT (0.64) | SMN1; SMN2MAPTMAPK1HSD17B1LMNA | |
| Bromobenzene SCHEMBL27532807 | 0.90 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPTALDH1A1LMNAHPGD | |
| Benzene SCHEMBL27947348 | 0.89 | MAPT (0.60) | SMN1; SMN2MAPTALDH1A1HSD17B1LMNA | |
| SCHEMBL51207 | 0.89 | MAPT (1.00) | SMN1; SMN2MAPTALDH1A1HSD17B1LMNA | |
| SCHEMBL7738989 | 0.89 | MAPT (1.00) | SMN1; SMN2MAPTALDH1A1HSD17B1LMNA | |
| SCHEMBL7252924 | 0.89 | MAPT (1.00) | SMN1; SMN2MAPTALDH1A1HSD17B1LMNA | |
| Hydrogen Sulfide SCHEMBL28388826 | 0.87 | MAPT (0.95) | SMN1; SMN2MAPTALDH1A1HSD17B1LMNA | |
| Water SCHEMBL9631565 | 0.87 | MAPT (0.95) | SMN1; SMN2MAPTALDH1A1HSD17B1LMNA | |
| Formaldehyde SCHEMBL7590040 | 0.85 | MAPT (0.91) | SMN1; SMN2MAPTALDH1A1HSD17B1LMNA | |
| SCHEMBL17187852 | 0.85 | CES2 (0.62) | SMN1; SMN2MAPTMAPK1HSD17B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707994-A | USEFUL AS A PLATELET AGGREGATION INHIBITOR, CANCER METASTASIS INHIBITOR, WOUND HEALING AGENT OR A BONE RESORPTION INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0725059-A1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-08-07 | — | — | EP | disclosed |