SCHEMBL177294

SCHEMBL177294

CC(=O)c1ccc(-c2ccc(Br)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.64
HSD17B1 P14061 2/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
MAOB P27338 1/20 0.55
CES2 O00748 1/20 0.54
CES1 P23141 1/20 0.54
RAB9A P51151 3/20 0.51
NPC1 O15118 1/20 0.51
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
KIF11 P52732 1/20 0.50
HAO1 Q9UJM8 1/20 0.50
XDH P47989 1/20 0.48
KMT2A Q03164 3/20 0.48
HPGD P15428 2/20 0.48
LMNA P02545 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
MEN1 O00255 2/20 0.48
GSK3B P49841 1/20 0.46
NQO2 P16083 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20102 0.93 CES2 (0.62) MAPTHSD17B1SMN1; SMN2MAOBCES2
SCHEMBL17187852 0.93 CES2 (0.62) MAPTHSD17B1SMN1; SMN2MAOBCES2
SCHEMBL8684103 0.92 SMN1; SMN2 (0.80) MAPTHSD17B1SMN1; SMN2MAOBRAB9A
Hydrochloric Acid SCHEMBL27695916 0.90 CES2 (0.59) MAPTHSD17B1SMN1; SMN2MAOBCES2
Water SCHEMBL28953297 0.90 CES2 (0.59) MAPTHSD17B1SMN1; SMN2MAOBCES2
Formaldehyde SCHEMBL28213355 0.88 CES2 (0.56) MAPTHSD17B1SMN1; SMN2MAOBCES2
Nitrogen SCHEMBL27858245 0.88 RAB9A (0.58) MAPTHSD17B1SMN1; SMN2MAOBCES2
Benzene SCHEMBL27947348 0.88 MAPT (0.60) MAPTHSD17B1SMN1; SMN2MAOBCES2
Ethylene SCHEMBL2169416 0.88 CES2 (0.56) MAPTHSD17B1SMN1; SMN2MAOBCES2
SCHEMBL197130 0.87 MAPT (0.80) MAPTHSD17B1SMN1; SMN2RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119039218-A Hemoglobin fluorescent probe, preparation method and application thereof 扬州大学 2024-11-29 CN claimed
CN-112645823-B Environment-friendly fluorine-containing surfactant and preparation method thereof 绍兴市上虞区武汉理工大学高等研究院 2022-07-05 CN claimed
CN-112645823-A Environment-friendly fluorine-containing surfactant and preparation method thereof 绍兴市上虞区武汉理工大学高等研究院 2021-04-13 CN claimed
JP-54048740-A None JP disclosed
US-20260042751-A1 AROMATIC HETEROCYCLIC DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO.,LTD. (JP) 2026-02-12 US disclosed
US-12516042-B2 Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2026-01-06 US disclosed
CN-119504464-A Novel compound for capping layer and organic light-emitting element comprising same 东进世美肯株式会社 2025-02-25 CN disclosed
US-20250040433-A1 AROMATIC HETEROCYCLIC DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO.,LTD. (JP) 2025-01-30 US disclosed
US-20250008837-A1 AROMATIC HETEROCYCLIC DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO.,LTD. (JP) 2025-01-02 US disclosed
CN-119039218-A Hemoglobin fluorescent probe, preparation method and application thereof 扬州大学 2024-11-29 CN disclosed
US-12089492-B2 Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2024-09-10 US disclosed
US-5137653-A Alkanoyl ester compounds and their intermediates and method of producing the same NIPPON MINING CO., LTD. (JP) 1992-08-11 US disclosed
US-5136013-A Polyesters BAYER AKTIENGESELLSCHAFT (DE) 1992-08-04 US disclosed
EP-0496378-A1 Biphenylderivatives, drugs containing these compounds and processes for their preparation Dr. Karl Thomae GmbH (DE) 1992-07-29 EP disclosed
EP-0311692-B1 NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION NIPPON MINING COMPANY LIMITED (JP) 1992-07-08 EP disclosed
US-5068300-A BIFUNCTIONAL STILBENE COMPOUNDS CONTAINING AT LEAST ONE Z-CONFIGURATED STILBENE GROUP, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF POLYMERS BAYER AKTIENGESELLSCHAFT (DE) 1991-11-26 US disclosed
EP-0425930-A2 Process for the preparation of symmetrical diarylacetylenes BAYER AG (DE) 1991-05-08 EP disclosed
EP-0391212-A2 Process for preparing bifunctional Z-stilbene compounds, new bifunctional Z-stilbene compounds and their use for preparing polymers BAYER AG (DE) 1990-10-10 EP disclosed
EP-0311692-A1 NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION NIPPON MINING COMPANY LIMITED (JP) 1989-04-19 EP disclosed
JP-S5448740-A BIPHENYL ESTERS SEIKO EPSON CORP 1979-04-17 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250008837-A1 AROMATIC HETEROCYCLIC DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT RER1, L1CAM, RUVBL1 MAPT 3905/4885HSD17B1 1836/4885SMN1; SMN2 2539/4885
US-20260042751-A1 AROMATIC HETEROCYCLIC DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT OXA1L, CCRL2, LOXL1 MAPT 4460/4885HSD17B1 1921/4885SMN1; SMN2 3323/4885
US-20250040433-A1 AROMATIC HETEROCYCLIC DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT RER1, L1CAM, ESR1 MAPT 3845/4885HSD17B1 1521/4885SMN1; SMN2 2448/4885
US-12089492-B2 Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element RER1, L1CAM, ESR1 MAPT 3845/4885HSD17B1 1521/4885SMN1; SMN2 2448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.