SCHEMBL8684262

SCHEMBL8684262

[O]c1ccc(Oc2ccc(Cl)cn2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPE Q05469 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.47
HTT P42858 1/20 0.47
SCN9A Q15858 3/20 0.44
HAO1 Q9UJM8 2/20 0.43
KDM4E B2RXH2 3/20 0.43
POLB P06746 1/20 0.43
ALDH1A1 P00352 1/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
HRH3 Q9Y5N1 1/20 0.42
LTA4H P09960 1/20 0.42
LMNA P02545 1/20 0.42
CYP2C9 P11712 1/20 0.42
TSHR P16473 1/20 0.42
APEX1 P27695 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
FPR2 P25090 1/20 0.41
HSPB1 P04792 1/20 0.41
CYP3A4 P08684 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5649724 0.81 MAPK1 (0.56) LIPEL3MBTL1HTTSCN9AHAO1
SCHEMBL24664854 0.81 LIPE (0.48) LIPEL3MBTL1HTTSCN9AHAO1
SCHEMBL7304855 0.81 LIPE (0.48) LIPEL3MBTL1HTTSCN9AHAO1
SCHEMBL12386850 0.81 KDM4E (0.58) LIPEL3MBTL1HTTHAO1KDM4E
SCHEMBL5370044 0.81 KDM4E (0.59) LIPEL3MBTL1HTTSCN9AHAO1
SCHEMBL20325535 0.81 LIPE (0.48) LIPEL3MBTL1HTTSCN9AHAO1
SCHEMBL6791192 0.81 ALDH1A1 (0.62) LIPEL3MBTL1HTTSCN9AHAO1
SCHEMBL6840382 0.80 LIPE (0.56) LIPESCN9AMEN1KMT2AHRH3
SCHEMBL20836099 0.80 LIPE (0.53) LIPESCN9AMEN1KMT2AHRH3
SCHEMBL3100106 0.79 LIPE (0.46) LIPEL3MBTL1HTTSCN9AHAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5712226-A Optically active D-pyridyloxy phenoxy propionate herbicides HOECHST AKTIENGESELLSCHAFT (DE) 1998-01-27 US disclosed