SCHEMBL8684467

SCHEMBL8684467

Oc1ccc(Oc2ccc(C(F)(F)F)cc2Cl)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.61
MEN1 O00255 1/20 0.53
TTR P02766 1/20 0.53
PPOX P50336 1/20 0.53
KMT2A Q03164 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
L3MBTL1 Q9Y468 2/20 0.48
RAB9A P51151 1/20 0.48
HTR2A P28223 3/20 0.46
SLC6A4 P31645 3/20 0.46
KCNH2 Q12809 3/20 0.46
MRGPRX4 Q96LA9 5/20 0.45
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
ATM Q13315 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11095176 0.92 FFAR1 (0.65) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL9711445 0.88 FFAR1 (0.53) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL10615136 0.88 FFAR1 (0.55) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL32669004 0.88 FFAR1 (0.55) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL10969104 0.87 FFAR1 (0.60) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL6238335 0.86 FFAR1 (0.51) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL15384989 0.84 HTR2A (0.59) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL8684464 0.84 FFAR1 (0.61) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL9582439 0.84 FFAR1 (0.58) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL11238861 0.84 L3MBTL1 (0.68) FFAR1MEN1TTRPPOXKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-54141767-A None JP disclosed
US-5712226-A Optically active D-pyridyloxy phenoxy propionate herbicides HOECHST AKTIENGESELLSCHAFT (DE) 1998-01-27 US disclosed
US-4755209-A Eradicating narrow-leaved weeds TEIJIN LIMITED (JP) 1988-07-05 US disclosed
US-4717417-A Certain 2-pyridyloxyphenoxypropanoic acid esters having herbicidal activity BAYER AKTIENGESELLSCHAFT (DE) 1988-01-05 US disclosed
EP-0112531-B1 OPTICALLY ACTIVE DERIVATIVES OF PHENOXYPROPIONIC ACID BAYER AG (DE) 1987-03-04 EP disclosed
US-4639537-A Certain laevorotatory p-tolysulfonyl or methanesulfonyl propionic acid ester intermediates BAYER AKTIENGESELLSCHAFT (DE) 1987-01-27 US disclosed
US-4596599-A Herbicides BAYER AKTIENGESELLSCHAFT (DE) 1986-06-24 US disclosed
US-4584396-A Substituted phenoxypropionates and herbicidal compositions NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1986-04-22 US disclosed
EP-0050019-B1 3-KETO-4-(4'-AROMATICALLY SUBSTITUTED-PHENOXY) COMPOUNDS, THEIR 3- ALKYLATED ENOL AND 2,3-HYDROGENATED DERIVATIVES AND THE USE THEREOF FOR THE CONTROL OF WEEDS SANDOZ AG (CH) 1986-04-09 EP disclosed
EP-0068260-B1 SUBSTITUTED PHENOXYPROPIONATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1986-03-05 EP disclosed
US-4289909-A Process for preparing 1-dichloroacyl-4-substituted phenoxy benzene and intermediates therefor CHEVRON RESEARCH (US) 1981-09-15 US disclosed
US-4287213-A Dichloroacyl diphenyl ether mite ovacides CHEVRON RESEARCH COMPANY (US) 1981-09-01 US disclosed
US-4270948-A (TRIFLUOROMETHYLPHENOXY)PHENOXYALKANE THIOCARBOXYLATE ISHIHARA SANGYO KAISHA LTD. (JP) 1981-06-02 US disclosed
US-4254262-A IN THE PRESENCE OF A QUATERNARY AMMONIUM OR PHOSPHONIUM SALT IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1981-03-03 US disclosed
EP-0005709-A1 Substituted diphenylether derivatives with herbicidal activity, herbicidal compositions containing them and their use CIBA-GEIGY AG (CH) 1979-12-12 EP disclosed
JP-S54141767-A PHENOXYPHENOXYALKYLOXAZOLINE DERIVATIVE AND HERBICIDES MITSUI TOATSU CHEM INC 1979-11-05 JP disclosed
US-4172959-A Process for the manufacture of diphenyl ethers HOECHST AKTIENGESELLSCHAFT (DE) 1979-10-30 US disclosed
US-4163661-A Phenoxyphenoxy crotonic acid derivatives and herbicidal composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1979-08-07 US disclosed
US-4070178-A Herbicidal diphenyl ethers ROHM AND HAAS COMPANY (US) 1978-01-24 US disclosed
US-3966826-A Phenyl ethers HOECHST AKTIENGESELLSCHAFT (DT) 1976-06-29 US disclosed