SCHEMBL8684464

SCHEMBL8684464

[O]c1ccc(Oc2ccc(C(F)(F)F)cc2Cl)cc1

nearest known ligand 0.72

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.61
MEN1 O00255 1/20 0.53
TTR P02766 1/20 0.53
PPOX P50336 1/20 0.53
KMT2A Q03164 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
L3MBTL1 Q9Y468 2/20 0.48
RAB9A P51151 1/20 0.48
HTR2A P28223 6/20 0.46
SLC6A4 P31645 6/20 0.46
KCNH2 Q12809 6/20 0.46
MAPT P10636 2/20 0.44
LMNA P02545 1/20 0.44
ATM Q13315 1/20 0.44
KDM4E B2RXH2 1/20 0.43
SCN8A Q9UQD0 1/20 0.43
SCN10A Q9Y5Y9 1/20 0.43
MRGPRX4 Q96LA9 1/20 0.42
EPAS1 Q99814 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11095176 0.92 FFAR1 (0.65) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL10969104 0.87 FFAR1 (0.60) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL11095342 0.84 FFAR1 (0.55) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL12937232 0.84 FFAR1 (0.58) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL2892190 0.84 FFAR1 (0.58) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL8684467 0.84 FFAR1 (0.61) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL9582439 0.84 FFAR1 (0.58) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL15384989 0.84 HTR2A (0.59) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL11238861 0.84 L3MBTL1 (0.68) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL9003844 0.83 FFAR1 (0.60) FFAR1MEN1TTRPPOXKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5712226-A Optically active D-pyridyloxy phenoxy propionate herbicides HOECHST AKTIENGESELLSCHAFT (DE) 1998-01-27 US disclosed