Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8686360 | 0.82 | GSK3A (0.48) | PIM1GSK3AGSK3BPOLBALDH1A1 | |
| SCHEMBL8685120 | 0.80 | PIM1 (0.60) | PIM1GSK3AGSK3BPOLBALDH1A1 | |
| SCHEMBL8687928 | 0.78 | PIM1 (0.51) | PIM1GSK3AGSK3BPOLBALDH1A1 | |
| SCHEMBL8691072 | 0.78 | PIM1 (0.72) | PIM1GSK3AGSK3BALDH1A1GAA | |
| SCHEMBL8685413 | 0.78 | GSK3A (0.49) | PIM1GSK3AGSK3BPOLBALDH1A1 | |
| SCHEMBL8686639 | 0.78 | PIM1 (0.48) | PIM1GSK3AGSK3BPOLBALDH1A1 | |
| SCHEMBL8688089 | 0.78 | PIM1 (0.61) | PIM1GSK3AGSK3BPOLBALDH1A1 | |
| SCHEMBL8685306 | 0.78 | PIM1 (0.48) | PIM1GSK3AGSK3BALDH1A1HTR2C | |
| SCHEMBL8685516 | 0.78 | ALDH1A1 (0.46) | PIM1GSK3AGSK3BPOLBALDH1A1 | |
| SCHEMBL8686647 | 0.77 | PIM1 (0.53) | PIM1GSK3AGSK3BPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |