Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 5/20 | 0.70 |
| ▸ | LTA4H | P09960 | 1/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | NOS1 | P29475 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265281 | 0.90 | CYP1A2 (0.67) | KMT2AKDM4EALDH1A1MAPK1NOS1 | |
| SCHEMBL10370478 | 0.83 | TBXAS1 (1.00) | TBXAS1LTA4HKMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9996050 | 0.81 | TBXAS1 (0.97) | TBXAS1LTA4HKMT2AKDM4EALDH1A1 | |
| SCHEMBL7590379 | 0.81 | ALDH1A1 (0.60) | TBXAS1LTA4HCYP19A1KDM4EALDH1A1 | |
| SCHEMBL9451380 | 0.78 | TBXAS1 (0.68) | TBXAS1KMT2AKDM4EALDH1A1NOS1 | |
| SCHEMBL7132156 | 0.78 | LTA4H (1.00) | TBXAS1LTA4HKMT2AKDM4EALDH1A1 | |
| SCHEMBL12382 | 0.78 | KMT2A (0.87) | TBXAS1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL1928520 | 0.78 | TBXAS1 (0.68) | TBXAS1KMT2AKDM4EALDH1A1NOS1 | |
| SCHEMBL3581172 | 0.78 | ALDH1A1 (0.85) | TBXAS1KMT2AKDM4EALDH1A1MAPK1 | |
| SCHEMBL11977009 | 0.78 | TBXAS1 (0.63) | TBXAS1KMT2AKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708171-A | HISTAMINE H3-RECEPTOR ANTAGONIST | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-01-13 | — | — | US | claimed |
| JP-58018366-A | — | — | None | — | — | JP | disclosed |
| US-5708171-A | HISTAMINE H3-RECEPTOR ANTAGONIST | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-01-13 | — | — | US | disclosed |
| JP-S5818366-A | NOVEL 1-ARYLOXYETHYLIMIDAZOLE DERIVATIVE, ITS PREPARATION AND INHIBITOR OF BLOOD PLATELET AGGLUTINATION CONTAINING THE SAME | TEIJIN LTD | 1983-02-02 | — | — | JP | disclosed |