Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | POLB | P06746 | 1/20 | 0.75 |
| ▸ | ATP4A | P20648 | 1/20 | 0.69 |
| ▸ | ATP4B | P51164 | 1/20 | 0.69 |
| ▸ | QPCT | Q16769 | 1/20 | 0.68 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8686274 | 0.93 | NOS1 (1.00) | NOS1MEN1KMT2APOLBATP4A | |
| Hydrochloric Acid SCHEMBL2529362 | 0.86 | MEN1 (0.85) | NOS1MEN1KMT2APOLBQPCT | |
| SCHEMBL16417749 | 0.86 | MEN1 (1.00) | NOS1MEN1KMT2APOLBQPCT | |
| SCHEMBL8684902 | 0.84 | QPCT (0.73) | NOS1MEN1KMT2APOLBQPCT | |
| SCHEMBL24083739 | 0.81 | MEN1 (0.76) | NOS1MEN1KMT2APOLBQPCT | |
| SCHEMBL6302835 | 0.81 | QPCT (0.73) | NOS1MEN1KMT2APOLBQPCT | |
| SCHEMBL18837209 | 0.81 | QPCT (0.73) | NOS1MEN1KMT2APOLBQPCT | |
| SCHEMBL10457427 | 0.81 | QPCT (0.73) | NOS1MEN1KMT2APOLBQPCT | |
| SCHEMBL12834989 | 0.81 | QPCT (1.00) | NOS1MEN1KMT2APOLBQPCT | |
| SCHEMBL7877092 | 0.81 | NOS1 (0.67) | NOS1MEN1KMT2APOLBATP4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708171-A | HISTAMINE H3-RECEPTOR ANTAGONIST | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-01-13 | — | — | US | claimed |
| US-5708171-A | HISTAMINE H3-RECEPTOR ANTAGONIST | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-01-13 | — | — | US | disclosed |