SCHEMBL8685474

SCHEMBL8685474

O=C(O)Oc1c(O)ccc2ccccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.50
GAA P10253 2/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
GLA P06280 1/20 0.50
HPGD P15428 1/20 0.50
PTPN22 Q9Y2R2 1/20 0.48
LDHA P00338 1/20 0.46
ERN1 O75460 1/20 0.46
POLB P06746 2/20 0.46
G6PD P11413 1/20 0.45
USP2 O75604 1/20 0.44
PAK1 Q13153 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
ABCG2 Q9UNQ0 1/20 0.44
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
WDR5 P61964 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5675873 0.84 KDM4E (0.54) HSD17B10GAAKDM4EALDH1A1GLA
SCHEMBL7068984 0.81 NCEH1 (0.45) HSD17B10GAAKDM4EALDH1A1HPGD
SCHEMBL27940178 0.81 ERN1 (0.46) HSD17B10GAAKDM4EALDH1A1GLA
SCHEMBL7942009 0.80 TSHR (0.47) HSD17B10GAAKDM4EALDH1A1HPGD
SCHEMBL8153278 0.80 CYP2A6 (0.47) HSD17B10GAAKDM4EALDH1A1GLA
SCHEMBL9125063 0.80 HSD17B10 (0.59) HSD17B10GAAKDM4EALDH1A1GLA
SCHEMBL51413 0.79 MEN1 (0.42) KDM4EALDH1A1HPGDLDHACYP1A2
SCHEMBL3999298 0.79 ALDH1A1 (0.55) HSD17B10GAAKDM4EALDH1A1GLA
SCHEMBL998061 0.78 ELANE (0.42) HSD17B10GAAKDM4EALDH1A1GLA
SCHEMBL70005 0.78 PTPN22 (0.58) HSD17B10GAAKDM4EALDH1A1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0829522-A1 Process for the preparation of quinophthalones BAYER AG (DE) 1998-03-18 EP disclosed
EP-0360163-B1 Aromatic carboxylic-acid derivatives and their use in combating the growth of undesirable plants BASF AG (DE) 1994-01-12 EP disclosed
EP-0360163-A2 Aromatic carboxylic-acid derivatives and their use in combating the growth of undesirable plants BASF Aktiengesellschaft (DE) 1990-03-28 EP disclosed
US-4439512-A BLOCKED 2,3-DIHYDROXYNAPHTHALENES LA CELLOPHANE (FR) 1984-03-27 US disclosed