Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15617683 | 0.69 | LMNA (0.45) | LMNAGLAALDH1A1KMT2ANPSR1 | |
| SCHEMBL9377878 | 0.69 | LMNA (0.45) | LMNAGLAALDH1A1KMT2ANPSR1 | |
| SCHEMBL9372316 | 0.67 | LMNA (0.40) | LMNAGLAALDH1A1KMT2ANPSR1 | |
| SCHEMBL28226342 | 0.65 | LMNA (0.51) | LMNAGLAALDH1A1KMT2ANPSR1 | |
| SCHEMBL1314765 | 0.64 | — | — | |
| Aminothiazole SCHEMBL5562412 | 0.61 | ALDH1A1 (0.75) | LMNAALDH1A1KMT2ANPSR1HSD17B10 | |
| SCHEMBL23163212 | 0.61 | TLR8 (0.37) | LMNAALDH1A1KMT2ATSHRCYP1A2 | |
| SCHEMBL16794591 | 0.60 | LMNA (0.54) | LMNAGLAALDH1A1KMT2ANPSR1 | |
| SCHEMBL1245039 | 0.60 | LMNA (0.46) | LMNAGLAALDH1A1KMT2AHSD17B10 | |
| SCHEMBL16198389 | 0.60 | LMNA (0.58) | LMNAGLAALDH1A1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714503-A | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 1998-02-03 | — | — | US | disclosed |