Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 14/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8704127 | 0.98 | L3MBTL1 (0.33) | SLC6A3SLC6A2SLC6A4L3MBTL1ALDH1A1 | |
| SCHEMBL8680858 | 0.90 | FAAH (0.39) | FAAHL3MBTL1ALDH1A1 | |
| SCHEMBL8681176 | 0.89 | FAAH (0.44) | FAAHL3MBTL1ALDH1A1 | |
| SCHEMBL8682086 | 0.87 | FAAH (0.47) | FAAHL3MBTL1ALDH1A1 | |
| SCHEMBL8680766 | 0.87 | FAAH (0.47) | FAAHL3MBTL1ALDH1A1 | |
| SCHEMBL8685986 | 0.87 | FAAH (0.47) | FAAHL3MBTL1ALDH1A1 | |
| SCHEMBL8681039 | 0.87 | FAAH (0.47) | FAAHL3MBTL1ALDH1A1 | |
| SCHEMBL8686103 | 0.87 | FAAH (0.47) | FAAHL3MBTL1ALDH1A1 | |
| SCHEMBL8680958 | 0.87 | FAAH (0.47) | FAAHL3MBTL1ALDH1A1 | |
| SCHEMBL8680888 | 0.87 | FAAH (0.47) | FAAHL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843983-A | Diphenylethane compounds containing a saturated heterocyclic group, their preparation, and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0844000-A1 | Use of alpha, omega-diarylalkane derivatives in the treatment and prevention of psychosis | SANKYO COMPANY LIMITED (JP) | 1998-05-27 | — | — | EP | disclosed |
| EP-0790235-A1 | Diaryl alkane derivatives containing an alicyclic group, their preparation and their therapeutic and prophylactic uses | SANKYO COMPANY LIMITED (JP) | 1997-08-20 | — | — | EP | disclosed |
| US-5556864-A | TREATMENT OF CIRCULATORY DISEASES AND PSYCHOSIS | SANKYO COMPANY, LIMITED (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0600717-A1 | Phenoxyalkylamines, -pyrrolidines and -piperidines for the treatment and prevention of circulatory diseases and psychosis | SANKYO COMPANY LIMITED (JP) | 1994-06-08 | — | — | EP | disclosed |