Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2696817 | 0.81 | GABRA1 (0.39) | GABRA1GABRB2CCR1CCR5CCR8 | |
| SCHEMBL1952444 | 0.81 | GABRA1 (0.38) | GABRA1GABRB2CYP3A4RXFP1MAPK1 | |
| SCHEMBL12051931 | 0.79 | RXFP1 (0.36) | RXFP1CCR1CCR5CCR8NOS3 | |
| SCHEMBL27069703 | 0.75 | GABRA1 (0.34) | GABRA1GABRB2CYP3A4TRPA1CCR1 | |
| SCHEMBL24455258 | 0.73 | NOS2 (0.40) | GABRA1GABRB2CYP3A4TRPA1NOS3 | |
| SCHEMBL295649 | 0.73 | CYP3A4 (0.50) | GABRA1GABRB2CYP3A4TRPA1MAPK1 | |
| SCHEMBL9643667 | 0.71 | GABRA1 (0.44) | GABRA1GABRB2CYP3A4TRPA1MAPK1 | |
| SCHEMBL160980 | 0.69 | GABRA1 (0.52) | GABRA1GABRB2CYP3A4TRPA1MAPK1 | |
| SCHEMBL7330225 | 0.69 | GABRA1 (0.42) | GABRA1GABRB2CYP3A4TRPA1MAPK1 | |
| SCHEMBL30390691 | 0.69 | GABRA1 (0.52) | GABRA1GABRB2CYP3A4TRPA1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1047777-C | Pyridyl tetrazolinone derivatives, and preparation method, composition and application thereof | BAYER AGROCHEM KK (JP) | 1999-12-29 | — | — | CN | disclosed |
| CN-1224014-A | Pyridyltetrazolinone derivatives | BAYER AGROCHEM KK (JP) | 1999-07-28 | — | — | CN | disclosed |
| US-5710278-A | Herbicidal 1-pyridyltetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1998-01-20 | — | — | US | disclosed |
| US-5641727-A | Herbicidal 1-pyridyltetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1997-06-24 | — | — | US | disclosed |
| CN-1121918-A | 1-pyridyltetrazolinone derivatives | BAYER AGROCHEM KK (JP) | 1996-05-08 | — | — | CN | disclosed |
| EP-0692482-A2 | 1-pyridyltetrazolinone derivatives | NIHON BAYER AGROCHEM K.K. (JP) | 1996-01-17 | — | — | EP | disclosed |