Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | TYK2 | P29597 | 1/20 | 0.48 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166603 | 0.79 | HPGD (0.54) | HPGDERCC5FEN1HTTSMN1; SMN2 | |
| SCHEMBL333141 | 0.79 | CYP3A4 (0.55) | HPGDERCC5FEN1HTTSMN1; SMN2 | |
| SCHEMBL29387256 | 0.79 | CYP3A4 (0.55) | HPGDERCC5FEN1HTTSMN1; SMN2 | |
| SCHEMBL29425530 | 0.79 | HPGD (0.54) | HPGDERCC5FEN1HTTSMN1; SMN2 | |
| Toluic Acid SCHEMBL29119772 | 0.78 | ALDH1A1 (0.59) | HPGDERCC5FEN1HTTSMN1; SMN2 | |
| SCHEMBL10669335 | 0.77 | CYP3A4 (0.59) | HPGDERCC5FEN1HTTSMN1; SMN2 | |
| SCHEMBL112406 | 0.77 | HPGD (0.57) | HPGDTYK2ERCC5FEN1HTT | |
| Toluic Acid SCHEMBL4152 | 0.77 | ALDH1A1 (0.65) | HPGDERCC5FEN1SMN1; SMN2MYC | |
| SCHEMBL49951 | 0.77 | HPGD (0.52) | HPGDERCC5FEN1HTTSMN1; SMN2 | |
| Toluic Acid SCHEMBL148201 | 0.77 | ALDH1A1 (0.65) | HPGDERCC5FEN1SMN1; SMN2MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780490-A | A O-(2,4-OXA(OR THIA)ZOLIDINYL)PHENYLOXY(OR THIO OR AMINO) ALKYLOXIME; ALDOSE REDUCTASE INHIBITORS; ANTIDIABETIC AND -HYPOGLYCEMIC AGENTS; LIVER, SKIN AND UROGENITAL DISORDERS | SANKYO COMPANY, LIMITED (JP) | 1998-07-14 | — | — | US | disclosed |