Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | GOT1 | P17174 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8687208 | 0.76 | TACR1 (0.36) | TRPV1GOT1KCNN4MEN1KMT2A | |
| SCHEMBL8692539 | 0.76 | C5AR1 (0.39) | TRPV1GOT1KCNN4HTTMEN1 | |
| SCHEMBL8686401 | 0.65 | HPGDS (0.35) | KMT2AALDH1A1 | |
| SCHEMBL8687690 | 0.65 | MEN1 (0.40) | HTTMEN1KMT2AJAK2TYK2 | |
| SCHEMBL8688260 | 0.64 | CGAS (0.41) | TRPV1GOT1FEN1CA1CA2 | |
| SCHEMBL8687053 | 0.64 | HTR1D (0.33) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL8687128 | 0.64 | MEN1 (0.38) | TRPV1GOT1HTTMEN1KMT2A | |
| SCHEMBL28207032 | 0.64 | ESR1 (0.54) | ESR1HTR6AKR1B1CA1CA2 | |
| SCHEMBL8686712 | 0.64 | TACR1 (0.40) | TRPV1GOT1HTTMEN1KMT2A | |
| SCHEMBL8687897 | 0.63 | KAT2B (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |