Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 10/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8692539 | 0.86 | C5AR1 (0.39) | TACR1TRPV1MEN1ALDH1A1MAPT | |
| SCHEMBL8687128 | 0.78 | MEN1 (0.38) | TACR1TRPV1MEN1ALDH1A1MAPT | |
| SCHEMBL8686707 | 0.76 | TRPV1 (0.37) | TRPV1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8686401 | 0.74 | HPGDS (0.35) | CYP19A1KDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL8687690 | 0.74 | MEN1 (0.40) | TACR1KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL8687053 | 0.73 | HTR1D (0.33) | CYP19A1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8687826 | 0.71 | CTNNB1 (0.39) | TACR1MEN1ALDH1A1TP53CYP1A2 | |
| SCHEMBL8687897 | 0.71 | KAT2B (0.37) | CYP19A1 | |
| SCHEMBL8686941 | 0.69 | CYP19A1 (0.33) | CYP19A1KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL8689993 | 0.62 | NLRP3 (0.49) | TACR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |