Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 3/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | GOT1 | P17174 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 2/20 | 0.33 |
| ▸ | CCR2 | P41597 | 2/20 | 0.33 |
| ▸ | CCR4 | P51679 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8692541 | 0.76 | C5AR1 (0.41) | TACR1DAOTRPV1MEN1MAPT | |
| SCHEMBL25267668 | 0.73 | CA1 (0.48) | LMNAALDH1A1HTR6MEN1MAPT | |
| SCHEMBL8687062 | 0.64 | DAO (0.39) | TACR1DAOMEN1MAPTKMT2A | |
| SCHEMBL25242608 | 0.64 | CYP19A1 (0.55) | HTR6 | |
| SCHEMBL8686707 | 0.64 | TRPV1 (0.37) | TRPV1ALDH1A1HTR6JAK2TYK2 | |
| SCHEMBL8687698 | 0.64 | TACR1 (0.49) | TACR1TRPV1LMNAMEN1MAPT | |
| SCHEMBL8688260 | 0.64 | CGAS (0.41) | TRPV1LMNAGOT1 | |
| SCHEMBL8687131 | 0.62 | TACR1 (0.53) | TACR1TRPV1MEN1MAPTKMT2A | |
| SCHEMBL8686947 | 0.61 | MAPT (0.37) | DAOLMNAALDH1A1MEN1MAPT | |
| SCHEMBL8688256 | 0.61 | CISD1 (0.39) | TRPV1JAK2TYK2JAK3GOT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |