Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8414528 | 0.96 | SLC6A4 (0.48) | SLC6A4MEN1KMT2A | |
| SCHEMBL1257677 | 0.85 | SLC6A4 (0.49) | SLC6A4OPRD1 | |
| SCHEMBL1257675 | 0.85 | SLC6A4 (0.49) | SLC6A4OPRD1 | |
| SCHEMBL10682307 | 0.82 | MEN1 (0.62) | SLC6A4MEN1KMT2A | |
| SCHEMBL5967865 | 0.82 | OPRD1 (0.51) | SLC6A4MEN1KMT2AOPRD1SIGMAR1 | |
| SCHEMBL11969174 | 0.82 | OPRD1 (0.51) | SLC6A4MEN1KMT2AOPRD1SIGMAR1 | |
| SCHEMBL11969306 | 0.81 | SIGMAR1 (0.62) | OPRD1SIGMAR1 | |
| SCHEMBL4331465 | 0.81 | SIGMAR1 (0.62) | OPRD1SIGMAR1 | |
| SCHEMBL13267225 | 0.81 | OPRD1 (0.50) | SLC6A4MEN1KMT2AOPRD1SIGMAR1 | |
| SCHEMBL11990438 | 0.81 | OPRD1 (0.56) | SLC6A4MEN1KMT2AOPRD1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108409738-B | 3, 4-methylenedioxyphenyl substituted tetrahydro-beta-carboline piperazine diketone derivative and application thereof | 华东理工大学 | 2020-10-16 | — | — | CN | disclosed |
| US-5834499-A | TREATING GASTROINTESTINAL DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-11-10 | — | — | US | disclosed |
| CN-1143364-A | 5-HT3 receptor agonist, novel thiazole derivative, and intermediate thereof | YAMANOUCHI PHARMA CO LTD (JP) | 1997-02-19 | — | — | CN | disclosed |
| EP-0749966-A1 | 5-HT 3 RECEPTOR AGONIST, NOVEL THIAZOLE DERIVATIVE, AND INTERMEDIATE THEREFOR | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-12-27 | — | — | EP | disclosed |