Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8686947 | 0.80 | MAPT (0.37) | DAOMAPTGAAOPRM1OPRK1 | |
| SCHEMBL8692541 | 0.70 | C5AR1 (0.41) | DAOMAPTOPRM1OPRK1OPRL1 | |
| SCHEMBL8686712 | 0.64 | TACR1 (0.40) | DAOMAPTOPRM1OPRK1OPRL1 | |
| SCHEMBL8686390 | 0.63 | AKR1B1 (0.41) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL8687818 | 0.59 | MAPT (0.44) | DAOMAPTNPSR1 | |
| SCHEMBL25212919 | 0.59 | HPGD (0.56) | RAB9AROCK2ROCK1 | |
| SCHEMBL27694476 | 0.59 | DAO (0.48) | DAOMAPTGAAMEN1KMT2A | |
| SCHEMBL2330607 | 0.59 | OPRM1 (0.44) | DAOMAPTGAAOPRM1OPRK1 | |
| SCHEMBL10502443 | 0.58 | DAO (0.44) | DAOMAPTGAAOPRM1OPRK1 | |
| SCHEMBL2633083 | 0.58 | DAO (0.50) | DAOMAPTOPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |