Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 5/20 | 0.41 |
| ▸ | TACR1 | P25103 | 5/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.35 |
| ▸ | GLRB | P48167 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8687698 | 0.88 | TACR1 (0.49) | TACR1KMT2AMEN1MAPTTRPV1 | |
| SCHEMBL8687830 | 0.79 | TACR1 (0.45) | TACR1KMT2AMEN1MAPTGLRA3 | |
| SCHEMBL8686712 | 0.76 | TACR1 (0.40) | TACR1DAOKMT2AMEN1MAPT | |
| SCHEMBL8687131 | 0.74 | TACR1 (0.53) | TACR1PPARGKMT2AMEN1MAPT | |
| SCHEMBL8688100 | 0.72 | ESRRA (0.44) | C5AR1 | |
| SCHEMBL8687062 | 0.70 | DAO (0.39) | TACR1DAOKMT2AMEN1MAPT | |
| SCHEMBL8686947 | 0.67 | MAPT (0.37) | DAOKMT2AMEN1MAPTHSD17B10 | |
| SCHEMBL8692539 | 0.66 | C5AR1 (0.39) | C5AR1TACR1DAOKMT2AMEN1 | |
| SCHEMBL8688098 | 0.64 | C5AR1 (0.38) | C5AR1KMT2ATRPV1HSD17B10ATM | |
| SCHEMBL8687249 | 0.63 | ESRRA (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |