Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 4/20 | 0.32 |
| ▸ | CNR1 | P21554 | 4/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL863364 | 0.83 | LTA4H (0.43) | HTTSMN1; SMN2CNR1LMNANR1I2 | |
| SCHEMBL15247276 | 0.79 | ALOX5 (0.33) | MEN1KMT2AHTTMAPTCYP3A4 | |
| SCHEMBL863202 | 0.76 | THRA (0.33) | MEN1KMT2AHTTMAPTCYP3A4 | |
| SCHEMBL12887140 | 0.73 | ALOX5 (0.36) | MEN1KMT2AHTTMAPTCYP3A4 | |
| SCHEMBL31516132 | 0.72 | PTPN11 (0.35) | MEN1KMT2AHTTSMN1; SMN2NPC1 | |
| SCHEMBL15724617 | 0.72 | ALOX5 (0.36) | MEN1KMT2AHTTMAPTCYP3A4 | |
| SCHEMBL15724614 | 0.70 | ALOX5 (0.39) | MEN1KMT2AHTTMAPTCYP3A4 | |
| SCHEMBL12622735 | 0.70 | TYR (0.33) | MEN1KMT2AHTTMAPTCYP3A4 | |
| SCHEMBL12610315 | 0.69 | — | — | |
| SCHEMBL10021733 | 0.69 | ALOX5 (0.38) | MEN1KMT2AHTTMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8847068-B2 | Compositions, methods, and systems comprising poly(thiophenes) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-09-30 | — | — | US | disclosed |
| WO-2012044778-A1 | COMPOSITIONS, METHODS, AND SYSTEMS COMPRISING POLY(THIOPHENES) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-04-05 | — | — | WO | disclosed |
| US-20120073662-A1 | COMPOSITIONS, METHODS, AND SYSTEMS COMPRISING POLY(THIOPHENES) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-03-29 | — | — | US | disclosed |