Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | PRKDC | P78527 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3882353 | 0.69 | ALDH1A1 (0.48) | ALDH1A1PRKDCKMT2ATSHRMEN1 | |
| SCHEMBL3133239 | 0.69 | MAOA (0.49) | ALDH1A1KMT2AMEN1GAAMAPK1 | |
| SCHEMBL31060240 | 0.67 | PRKDC (1.00) | ALDH1A1PRKDCGAAAGTR1 | |
| SCHEMBL3880536 | 0.66 | ALDH1A1 (0.48) | ALDH1A1PRKDCKMT2ATSHRMEN1 | |
| SCHEMBL20887127 | 0.66 | PRKDC (0.54) | ALDH1A1PRKDCKMT2ATSHRMEN1 | |
| SCHEMBL27592893 | 0.65 | MAPT (0.41) | ALDH1A1KMT2AMEN1GAALMNA | |
| SCHEMBL8188021 | 0.65 | PTGS2 (0.51) | KMT2AMEN1GAAMAPTL3MBTL1 | |
| SCHEMBL28818224 | 0.64 | GAA (0.43) | ALDH1A1KMT2AMEN1GAAMAPK1 | |
| SCHEMBL13437711 | 0.64 | KDM5A (0.59) | ALDH1A1KMT2AMEN1GAAMAPT | |
| SCHEMBL12125216 | 0.63 | METAP1 (0.46) | ALDH1A1KMT2AMEN1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5833885-A | LENSES, ULTRAVIOLET RADIATION PROTECTION | PILKINGTON PLC (GB) | 1998-11-10 | — | — | US | disclosed |
| EP-0713491-A1 | SPIRO(INDOLINO) OXAZINE PHOTOCHROMIC COMPOUNDS | PILKINGTON PLC (GB) | 1996-05-29 | — | — | EP | disclosed |
| WO-1995005385-A1 | SPIRO(INDOLINO) OXAZINE PHOTOCHROMIC COMPOUNDS | PILKINGTON PLC (GB) | 1995-02-23 | — | — | WO | disclosed |