Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8689444 | 0.84 | PTGES (0.49) | KDM4EPOLBALDH1A1HPGDTP53 | |
| SCHEMBL8691082 | 0.83 | KDM4E (0.51) | KDM4EPOLBALDH1A1HPGDGAA | |
| SCHEMBL8479917 | 0.80 | NPC1 (0.54) | KDM4EPOLBALDH1A1TP53NPC1 | |
| SCHEMBL8483600 | 0.80 | KDM4E (0.51) | KDM4EPOLBALDH1A1HPGDTP53 | |
| SCHEMBL8479161 | 0.80 | MAOA (0.42) | KDM4EPOLBTP53KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8480319 | 0.79 | NPC1 (0.53) | KDM4EPOLBTP53NPC1RAB9A | |
| SCHEMBL8113168 | 0.77 | SMN1; SMN2 (0.59) | KDM4EPOLBALDH1A1HPGDTP53 | |
| SCHEMBL13739299 | 0.76 | KMT2A (0.61) | KDM4EPOLBALDH1A1HPGDHTT | |
| SCHEMBL31219102 | 0.76 | KDM4E (0.67) | KDM4EPOLBALDH1A1HPGDTP53 | |
| SCHEMBL20139758 | 0.75 | KDM4E (0.55) | KDM4EPOLBALDH1A1HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741926-A | ANTIDIABETIC AGENT | SHAMAN PHARMACEUTICALS, INC. (US) | 1998-04-21 | — | — | US | disclosed |