Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | POLB | P06746 | 5/20 | 0.59 |
| ▸ | TP53 | P04637 | 4/20 | 0.59 |
| ▸ | CASP1 | P29466 | 2/20 | 0.59 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.59 |
| ▸ | CASP7 | P55210 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8832028 | 0.80 | NPC1 (0.65) | SMN1; SMN2NPC1RAB9APOLBTP53 | |
| SCHEMBL17274878 | 0.78 | MEN1 (0.51) | SMN1; SMN2NPC1RAB9APOLBTP53 | |
| SCHEMBL9706263 | 0.77 | CASP1 (0.65) | SMN1; SMN2NPC1RAB9APOLBTP53 | |
| SCHEMBL8689043 | 0.77 | KDM4E (0.54) | SMN1; SMN2NPC1RAB9APOLBTP53 | |
| SCHEMBL29572859 | 0.76 | RAB9A (1.00) | SMN1; SMN2NPC1RAB9APOLBTP53 | |
| SCHEMBL278729 | 0.76 | RAB9A (1.00) | SMN1; SMN2NPC1RAB9APOLBTP53 | |
| SCHEMBL29506296 | 0.75 | ALDH1A1 (0.63) | SMN1; SMN2NPC1RAB9APOLBTP53 | |
| SCHEMBL28389229 | 0.75 | ALDH1A1 (0.63) | SMN1; SMN2NPC1RAB9APOLBTP53 | |
| SCHEMBL9436884 | 0.75 | RAB9A (0.62) | SMN1; SMN2NPC1RAB9APOLBTP53 | |
| SCHEMBL17274929 | 0.75 | ACHE (0.46) | SMN1; SMN2NPC1RAB9APOLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037638-A1 | AGENTS | Lundblad, Leif J., I. (SE) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999030712-A1 | AGENTS | LUNDBLAD, LEIF, J., I. (SE) | 1999-06-24 | — | — | WO | disclosed |