Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15267699 | 0.87 | KMT2A (0.60) | KMT2AMEN1GAAPOLBLMNA | |
| SCHEMBL1356115 | 0.86 | KMT2A (0.50) | KMT2AMEN1GAAPOLBLMNA | |
| SCHEMBL4787002 | 0.84 | KMT2A (0.51) | KMT2AMEN1GAAPOLBSMN1; SMN2 | |
| SCHEMBL4548528 | 0.82 | TPSAB1 (0.48) | KMT2AMEN1GAAPOLBHDAC3 | |
| SCHEMBL5362495 | 0.82 | HDAC3 (0.60) | KMT2AMEN1SMN1; SMN2LMNAHDAC3 | |
| SCHEMBL21765683 | 0.81 | NPC1 (0.50) | KMT2AMEN1GAAPOLBLMNA | |
| SCHEMBL8689095 | 0.81 | MEN1 (0.62) | KMT2AMEN1GAAPOLBSMN1; SMN2 | |
| SCHEMBL6029960 | 0.80 | GAA (0.59) | KMT2AMEN1GAAPOLBSMN1; SMN2 | |
| SCHEMBL1039601 | 0.79 | KMT2A (0.76) | KMT2AMEN1SMN1; SMN2LMNAHTT | |
| SCHEMBL7888049 | 0.79 | CYP1A1 (0.60) | KMT2AMEN1GAAPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821249-A | Anhydroecogonine compounds and their use as anticholinergic agents | UNIVERSITY OF ROCHESTER (US) | 1998-10-13 | — | — | US | claimed |