Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8822548 | 0.89 | HTR1A (0.62) | DRD3 | |
| Hydrochloric Acid SCHEMBL8903720 | 0.88 | HTR1A (0.61) | DRD3 | |
| SCHEMBL7204936 | 0.80 | HTR1A (0.75) | — | |
| SCHEMBL7208781 | 0.80 | HTR1A (0.75) | — | |
| SCHEMBL8822596 | 0.79 | HTR1A (0.59) | DRD3 | |
| SCHEMBL9558614 | 0.79 | HTR1D (0.48) | DRD3 | |
| SCHEMBL8691952 | 0.77 | DRD3 (0.59) | DRD3 | |
| SCHEMBL8904245 | 0.77 | HTR1A (0.70) | DRD3 | |
| Hydrochloric Acid SCHEMBL8904219 | 0.76 | HTR1A (0.68) | DRD3 | |
| SCHEMBL7445447 | 0.76 | DRD2 (0.76) | DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708018-A | 2-aminoindans as selective dopamine D3 ligands | PHARMACIA & UPJOHN COMPANY (US) | 1998-01-13 | — | — | US | disclosed |
| EP-0712387-A1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 1996-05-22 | — | — | EP | disclosed |
| WO-1995004713-A1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | THE UPJOHN COMPANY (US) | 1995-02-16 | — | — | WO | disclosed |