Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | FABP4 | P15090 | 1/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.51 |
| ▸ | RBP4 | P02753 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8691586 | 0.85 | ALDH1A1 (0.70) | POLBGAAKMT2AALDH1A1RBP4 | |
| SCHEMBL6719470 | 0.84 | ALDH1A1 (0.57) | POLBGAAKMT2AALDH1A1MEN1 | |
| SCHEMBL8818735 | 0.84 | POLB (0.47) | POLBGAAKMT2AALDH1A1MEN1 | |
| SCHEMBL6719474 | 0.81 | POLB (0.62) | POLBGAAKMT2AALDH1A1MEN1 | |
| SCHEMBL8689403 | 0.81 | ALDH1A1 (0.59) | POLBKMT2AALDH1A1MEN1GRIK1 | |
| SCHEMBL8688769 | 0.81 | TRPA1 (0.55) | POLBTAS2R14KMT2AALDH1A1MEN1 | |
| SCHEMBL8691649 | 0.81 | ALDH1A1 (0.55) | POLBGAAKMT2AALDH1A1MEN1 | |
| SCHEMBL27546648 | 0.81 | GAA (0.65) | POLBGAATAS2R14KMT2AALDH1A1 | |
| SCHEMBL1462231 | 0.81 | GRIK1 (0.72) | POLBGAATAS2R14KMT2AALDH1A1 | |
| SCHEMBL2627998 | 0.79 | KMT2A (0.59) | POLBKMT2AALDH1A1MEN1FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741926-A | ANTIDIABETIC AGENT | SHAMAN PHARMACEUTICALS, INC. (US) | 1998-04-21 | — | — | US | claimed |
| WO-1997030019-A1 | ANILINE DERIVATIVES HAVING ANTIHYPERGLYCEMIC ACTIVITY | SHAMAN PHARMACEUTICALS, INC. (US) | 1997-08-21 | — | — | WO | claimed |
| US-5741926-A | ANTIDIABETIC AGENT | SHAMAN PHARMACEUTICALS, INC. (US) | 1998-04-21 | — | — | US | disclosed |
| WO-1997030019-A1 | ANILINE DERIVATIVES HAVING ANTIHYPERGLYCEMIC ACTIVITY | SHAMAN PHARMACEUTICALS, INC. (US) | 1997-08-21 | — | — | WO | disclosed |