Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | STAT1 | P42224 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721838 | 0.91 | RAB9A (0.65) | RAB9ANPSR1MAPTSTAT1POLB | |
| SCHEMBL8684478 | 0.87 | TDP1 (0.67) | RAB9ANPSR1MAPTSTAT1POLB | |
| SCHEMBL7631227 | 0.85 | RAB9A (0.64) | RAB9ANPSR1MAPTSTAT1POLB | |
| SCHEMBL8686608 | 0.81 | LMNA (0.38) | NPSR1TSHRKMT2ALMNAGAA | |
| SCHEMBL8689491 | 0.80 | RAB9A (0.57) | RAB9ANPSR1MAPTSTAT1POLB | |
| SCHEMBL8716791 | 0.80 | RAB9A (0.51) | RAB9ANPSR1MAPTSTAT1POLB | |
| SCHEMBL8684469 | 0.78 | RAB9A (0.49) | RAB9ANPSR1MAPTSTAT1POLB | |
| SCHEMBL9097901 | 0.77 | RAB9A (0.47) | RAB9ANPSR1MAPTSTAT1POLB | |
| SCHEMBL16316220 | 0.77 | RAB9A (0.78) | RAB9ANPSR1MAPTSTAT1POLB | |
| SCHEMBL7685888 | 0.76 | RAB9A (0.73) | RAB9ANPSR1MAPTSTAT1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756726-A | PHOTOSENSITIZERS | PHARMACYCLICS, INC. (US) | 1998-05-26 | — | — | US | disclosed |