SCHEMBL4826239

SCHEMBL4826239

O=[N+]([O-])c1ccc(OS(=O)(=O)Cl)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 8/20 0.67
CA2 P00918 8/20 0.67
CA9 Q16790 6/20 0.67
HTT P42858 1/20 0.56
HSPB1 P04792 2/20 0.53
CA12 O43570 5/20 0.50
CA7 P43166 3/20 0.48
CA14 Q9ULX7 3/20 0.48
CA3 P07451 2/20 0.48
CA4 P22748 2/20 0.48
CA6 P23280 2/20 0.48
CA5A P35218 2/20 0.48
CA13 Q8N1Q1 2/20 0.48
CA5B Q9Y2D0 2/20 0.48
ALDH1A1 P00352 3/20 0.48
HSP90AA1 P07900 1/20 0.48
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
MMP1 P03956 1/20 0.44
MMP2 P08253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL866410 0.83 CA1 (0.71) CA1CA2CA9HTTHSPB1
SCHEMBL7527679 0.81 CA1 (0.62) CA1CA2CA9HTTHSPB1
SCHEMBL866411 0.80 CA1 (0.67) CA1CA2CA9HTTHSPB1
SCHEMBL3519559 0.80 CA2 (1.00) CA1CA2CA9HTTCA12
SCHEMBL31634023 0.80 CA1 (0.67) CA1CA2CA9HTTHSPB1
SCHEMBL8690274 0.80 CA1 (0.67) CA1CA2CA9HTTHSPB1
SCHEMBL11704991 0.80 CA1 (0.67) CA1CA2CA9HTTHSPB1
Potassium Ion SCHEMBL1902294 0.80 CA1 (0.67) CA1CA2CA9HTTHSPB1
SCHEMBL17318171 0.80 CA1 (0.67) CA1CA2CA9HTTHSPB1
Sulfuric Acid SCHEMBL3198737 0.78 CA1 (0.65) CA1CA2CA9HTTHSPB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747231-A1 LIPIDS AND LIPID NANOPARTICLES Geneditbio Limited (HK) 2026-05-27 EP disclosed
EP-4211146-B1 SYNTHETIC CYCLIC PEPTIDE MIMETICS UNIV BAR ILAN (IL) 2026-05-20 EP disclosed
US-12616760-B2 Synthetic cyclic peptide mimetics BAR ILAN UNIVERSITY (IL) 2026-05-05 US disclosed
EP-4725941-A1 ARYLAMIDE DERIVATIVE HAVING ANTITUMOR ACTIVITY CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2026-04-15 EP disclosed
EP-4702010-A1 PHOTOACTIVE COMPOUNDS Merck Patent GmbH (DE) 2026-03-04 EP disclosed
US-20250262298-A1 STING MODULATOR COMPOUNDS WITH SULFAMATE LINKAGES, AND METHODS OF MAKING AND USING TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-08-21 US disclosed
CN-114751950-B Cyclic dinucleotide compounds and methods of use 免疫传感器公司 2025-04-18 CN disclosed
WO-2025016446-A1 LIPIDS AND LIPID NANOPARTICLES GENEDITBIO LIMITED (CN) 2025-01-23 WO disclosed
CN-115803024-B Compositions comprising aryl amide derivatives 中外制药株式会社 2025-01-10 CN disclosed
CN-114929669-B Aryl amide derivatives with antitumor activity 中外制药株式会社 2024-11-29 CN disclosed
US-5086128-A HIGH MOLECULAR WEIGHT ARYLENE SULPHIDE POLYMER MELT MIXED WITH AROMATIC NITRO COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1992-02-04 US disclosed
EP-0309912-B1 Process for the preparation of alkylated dodecahydro-naphtho[2,1-B]furans BASF Aktiengesellschaft (DE) 1991-05-15 EP disclosed
EP-0370953-A2 Process for the preparation of dye intermediates CIBA-GEIGY AG (CH) 1990-05-30 EP disclosed
EP-0309912-A1 Process for the preparation of alkylated dodecahydro-naphtho[2,1-B]furans BASF Aktiengesellschaft (DE) 1989-04-05 EP disclosed
US-4388246-A THERMAL SPLITTING OF CARBAMATES BAYER AKTIENGESELLSCHAFT (DE) 1983-06-14 US disclosed
US-4379784-A ANTIBIOTICS DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1983-04-12 US disclosed
EP-0010249-A2 Herbicidal agents, process for their preparation and their use in combating weeds BAYER AG (DE) 1980-04-30 EP disclosed
EP-0010250-A2 Use of Sulfonanilides in inhibition of plant growth BAYER AG (DE) 1980-04-30 EP disclosed
US-4150223-A ANTIBIOTICS MERCK & CO., INC. (US) 1979-04-17 US disclosed
US-4032521-A ANTIBIOTICS MERCK & CO., INC. (US) 1977-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616760-B2 Synthetic cyclic peptide mimetics TPX2, IAPP, HAX1 CA1 208/4885CA2 2097/4885CA9 792/4885
US-20250262298-A1 STING MODULATOR COMPOUNDS WITH SULFAMATE LINKAGES, AND METHODS OF MAKING AND USING STING1, CGAS, TBK1 CA1 4276/4885CA2 2144/4885CA9 3393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.