SCHEMBL8690276

SCHEMBL8690276

CCCCn1nc(CC)c(C(=O)OC)c1Cc1ccc(Br)cc1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8696229 0.93 TP53 (0.36) TP53MAPT
SCHEMBL8693926 0.91 HRH1 (0.35)
SCHEMBL8694551 0.88 FPR1 (0.40)
SCHEMBL8692841 0.84 HRH1 (0.36) TP53MAPT
SCHEMBL8690998 0.83 CNR2 (0.38)
SCHEMBL8692878 0.83 HTT (0.43)
SCHEMBL8695154 0.81 FPR1 (0.41)
SCHEMBL8695782 0.78 HTT (0.40) MAPT
SCHEMBL8694977 0.78 NPC1 (0.34)
SCHEMBL8691422 0.77 CNR2 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5827863-A Pyrazole derivatives as angiotensin II antagonists J. URIACH & CIA, S.A. (ES) 1998-10-27 US disclosed
EP-0721454-A1 NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST J. URIACH & CIA. S.A. (ES) 1996-07-17 EP disclosed
WO-1996004273-A1 NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST J. URIACH & CIA, S.A. (ES) 1996-02-15 WO disclosed