Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690276 | 0.93 | TP53 (0.35) | TP53MAPT | |
| SCHEMBL8692841 | 0.91 | HRH1 (0.36) | TP53MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8695154 | 0.87 | FPR1 (0.41) | — | |
| SCHEMBL8693926 | 0.84 | HRH1 (0.35) | — | |
| SCHEMBL8694977 | 0.84 | NPC1 (0.34) | NPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL8693539 | 0.82 | FPR1 (0.37) | NPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL8694551 | 0.81 | FPR1 (0.40) | — | |
| SCHEMBL8693020 | 0.80 | ALDH1A1 (0.47) | MAPTSMN1; SMN2 | |
| SCHEMBL8691277 | 0.80 | ALDH1A1 (0.47) | MAPTSMN1; SMN2 | |
| SCHEMBL8691408 | 0.77 | FPR1 (0.42) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827863-A | Pyrazole derivatives as angiotensin II antagonists | J. URIACH & CIA, S.A. (ES) | 1998-10-27 | — | — | US | disclosed |
| EP-0721454-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA. S.A. (ES) | 1996-07-17 | — | — | EP | disclosed |