Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | FPR1 | P21462 | 2/20 | 0.34 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693926 | 0.93 | HRH1 (0.35) | HRH1 | |
| SCHEMBL8696229 | 0.91 | TP53 (0.36) | RAB9ANPC1SMN1; SMN2NPSR1TP53 | |
| SCHEMBL8693539 | 0.87 | FPR1 (0.37) | HRH1RAB9ANPC1SMN1; SMN2NPSR1 | |
| SCHEMBL8690276 | 0.84 | TP53 (0.35) | TP53MAPT | |
| SCHEMBL8695154 | 0.82 | FPR1 (0.41) | FPR1FPR2 | |
| SCHEMBL8690998 | 0.81 | CNR2 (0.38) | HRH1FPR1FPR2 | |
| SCHEMBL8693020 | 0.80 | ALDH1A1 (0.47) | SMN1; SMN2MAPT | |
| SCHEMBL8691277 | 0.80 | ALDH1A1 (0.47) | SMN1; SMN2MAPT | |
| SCHEMBL8694583 | 0.80 | LMNA (0.39) | RAB9ASMN1; SMN2HSP90AA1HSP90B1FPR1 | |
| SCHEMBL8694977 | 0.80 | NPC1 (0.34) | RAB9ANPC1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827863-A | Pyrazole derivatives as angiotensin II antagonists | J. URIACH & CIA, S.A. (ES) | 1998-10-27 | — | — | US | disclosed |