Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690321 | 0.87 | AR (0.51) | TSHRLMNAALDH1A1SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL8691638 | 0.85 | AR (0.50) | TSHRLMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8690764 | 0.77 | ENPP2 (0.45) | ALDH1A1 | |
| SCHEMBL8691136 | 0.77 | KDM4E (0.52) | TSHRMEN1KMT2ALMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL8692936 | 0.76 | KDM4E (0.51) | TSHRMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL8694553 | 0.75 | MEN1 (0.56) | TSHRMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL26698239 | 0.74 | CHRM3 (0.55) | TSHRMEN1KMT2AALDH1A1POLB | |
| SCHEMBL7592805 | 0.74 | CHRM3 (0.57) | SMN1; SMN2 | |
| SCHEMBL630705 | 0.73 | KMT2A (0.70) | TSHRMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL4444477 | 0.73 | CYP2B6 (0.59) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789409-A | ANTIINFLAMMATORY AGENTS | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1998-08-04 | — | — | US | claimed |
| US-5789409-A | ANTIINFLAMMATORY AGENTS | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1998-08-04 | — | — | US | disclosed |