Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7636374 | 0.83 | KMT2A (0.54) | KMT2AMEN1MAPTS1PR4LMNA | |
| SCHEMBL14934928 | 0.80 | ALDH1A1 (0.61) | KMT2AMEN1MAPTMAPK1ALDH1A1 | |
| SCHEMBL6925456 | 0.80 | KMT2A (0.51) | KMT2AMEN1MAPTS1PR4LMNA | |
| SCHEMBL15964601 | 0.78 | KMT2A (0.49) | KMT2AMEN1MAPTS1PR4LMNA | |
| SCHEMBL10464057 | 0.76 | MEN1 (0.51) | KMT2AMEN1MAPTS1PR4LMNA | |
| SCHEMBL20109336 | 0.75 | MEN1 (0.49) | KMT2AMEN1MAPTS1PR4LMNA | |
| SCHEMBL22609299 | 0.74 | MEN1 (0.46) | KMT2AMEN1MAPTS1PR4LMNA | |
| SCHEMBL4733 | 0.73 | CYP1A2 (0.55) | KMT2AMEN1MAPTS1PR4LMNA | |
| SCHEMBL7633403 | 0.73 | L3MBTL1 (0.54) | KMT2AMEN1LMNAALDH1A1EGFR | |
| SCHEMBL449585 | 0.73 | KMT2A (0.50) | KMT2AMEN1MAPTS1PR4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827863-A | Pyrazole derivatives as angiotensin II antagonists | J. URIACH & CIA, S.A. (ES) | 1998-10-27 | — | — | US | disclosed |
| EP-0721454-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA. S.A. (ES) | 1996-07-17 | — | — | EP | disclosed |
| WO-1996004273-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA, S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |