SCHEMBL4733

SCHEMBL4733

CCOC(=O)Cc1ccc(Br)cc1

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.55
CYP2C9 P11712 1/20 0.55
CYP4Z1 Q86W10 1/20 0.54
POLB P06746 1/20 0.53
MAPT P10636 4/20 0.53
KMT2A Q03164 3/20 0.53
MEN1 O00255 2/20 0.53
LMNA P02545 2/20 0.53
S1PR4 O95977 1/20 0.53
S1PR1 P21453 1/20 0.53
MAPK1 P28482 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
ALDH1A1 P00352 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
HPGD P15428 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12987888 0.95 CYP1A2 (0.51) CYP1A2CYP2C9CYP4Z1POLBMAPT
SCHEMBL68851 0.90 CYP4Z1 (0.62) CYP4Z1POLBMAPTKMT2AMEN1
SCHEMBL4812296 0.86 KMT2A (0.48) CYP1A2CYP2C9CYP4Z1POLBMAPT
SCHEMBL1124344 0.85 CYP4Z1 (0.54) CYP4Z1POLBMAPTKMT2AMEN1
SCHEMBL68930 0.84 CYP4Z1 (0.57) CYP4Z1MAPTLMNAMAPK1ALDH1A1
SCHEMBL1107146 0.84 CYP4Z1 (0.57) CYP1A2CYP2C9CYP4Z1MAPTKMT2A
SCHEMBL10299459 0.84 CYP4Z1 (0.57) CYP4Z1POLBMAPTKMT2AMEN1
SCHEMBL6057577 0.84 CYP4F2 (0.59) CYP4Z1POLBMAPTKMT2AMEN1
SCHEMBL6207253 0.82 CYP4Z1 (0.55) CYP4Z1POLBMAPTKMT2AMEN1
SCHEMBL5545889 0.82 CYP4Z1 (0.55) CYP4Z1POLBMAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119080664-A Preparation method of Fu Kasai ethyl acetate 南京康立瑞生物科技有限公司 2024-12-06 CN claimed
CN-118184581-A Synthesis and application of Delta opioid receptor biased agonist compound and analgesic drug 中国科学院大连化学物理研究所 2024-06-14 CN claimed
CN-111511725-B 1-cyano-2- (4-cyclopropyl-benzyl) -4-) (beta-D-glucopyranos-1-yl) -benzene Synthesis of 1:1:1 Co-crystals of L-proline and Water 勃林格殷格翰维特梅迪卡有限公司 2024-04-09 CN claimed
EP-4309002-A1 RECORDING A LATENT HOLOGRAPHIC GRATING AND AMPLIFICATION OF ITS DYNAMIC RANGE META PLATFORMS TECHNOLOGIES, LLC (US) 2024-01-24 EP claimed
CN-117321088-A Preparation of monodisperse Polymer beads by Room temperature initiation 深圳华大基因科技有限公司 2023-12-29 CN claimed
CN-117305864-A alpha-Fe 2 O 3 Porphyrin-based MOFs core-shell photoelectric catalyst and preparation method and application thereof 石家庄铁道大学 2023-12-29 CN claimed
CN-108997526-B Synthesis method of azide group-containing copolymer 江南大学 2020-11-06 CN claimed
CN-111511725-A Synthesis of 1:1:1 cocrystals of 1-cyano-2- (4-cyclopropyl-benzyl) -4- (β -D-glucopyranos-1-yl) -benzene, L-proline and water 勃林格殷格翰维特梅迪卡有限公司 2020-08-07 CN claimed
CN-122010924-A Aminothiazole heterocyclic compound containing pyridone and synthesis and application thereof 浙江大学 2026-05-12 CN disclosed
EP-4727537-A2 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF Adaxion Therapeutics, Inc. (US) 2026-04-22 EP disclosed
US-20260092053-A1 KHK INHIBITORS GILEAD SCIENCES INC (US) 2026-04-02 US disclosed
CN-121735764-A Preparation method of ethyl 4-bromophenylacetate 上海北卡医药技术有限公司 2026-03-27 CN disclosed
CN-121735764-A Preparation method of ethyl 4-bromophenylacetate 上海北卡医药技术有限公司 2026-03-27 CN disclosed
EP-4695250-A1 TETRACYCLIC COMPOUNDS AS SMARCA2 AND/OR SMARCA4 DEGRADERS Aurigene Oncology Limited (IN) 2026-02-18 EP disclosed
US-4820715-A TREATING NAUSEA AND GASTRIC DISORDERS BRISTOL-MYERS COMPANY (US) 1989-04-11 US disclosed
US-4808624-A ANTIEMETICS BRISTOL-MYERS COMPANY (US) 1989-02-28 US disclosed
US-4417052-A ANTIINFLAMMATORY AGENTS; ANALGESICS; VIRICIDES STERLING DRUG INC. (US) 1983-11-22 US disclosed
US-4308382-A ANTIINFLAMMATORY AGENTS STERLING DRUG INC. (US) 1981-12-29 US disclosed
US-4279918-A ANTIDEPRESSANTS, STIMULANTS BYK GULDEN LOMBERG CHEMISCHE FABRIK G.M.B.H. (DE) 1981-07-21 US disclosed
US-4153724-A Benzoyl phenoxy acetic acid derivatives KAKEN CHEMICAL CO., LTD. (JP) 1979-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092053-A1 KHK INHIBITORS KHK, SLC5A2, HK1 CYP1A2 774/4885CYP2C9 377/4885CYP4Z1 2076/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.