Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8692600 | 0.88 | GNRHR (0.44) | GNRHR | |
| SCHEMBL8695361 | 0.79 | PTGS2 (0.43) | GNRHR | |
| SCHEMBL8698485 | 0.78 | MAPT (0.46) | — | |
| Hydrochloric Acid SCHEMBL8699214 | 0.77 | MAPT (0.45) | — | |
| SCHEMBL7997233 | 0.72 | GNRHR (0.50) | GNRHR | |
| SCHEMBL8689808 | 0.70 | CYP3A4 (0.64) | GNRHR | |
| SCHEMBL7995810 | 0.70 | GNRHR (0.54) | GNRHR | |
| Trimethylammonium SCHEMBL8695107 | 0.69 | HTR2A (0.51) | GNRHR | |
| SCHEMBL8692594 | 0.69 | GNRHR (0.56) | GNRHR | |
| Iodide SCHEMBL8695111 | 0.69 | GNRHR (0.47) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849764-A | Antagonists of gonadotropin releasing hormone | MERCK & CO., INC. (US) | 1998-12-15 | — | — | US | disclosed |
| US-5756507-A | TREATING SEX HORMONE RELATED DISORDERS | MERCK & CO., INC. (US) | 1998-05-26 | — | — | US | disclosed |