Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8699214 | 0.99 | MAPT (0.45) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL8695361 | 0.80 | PTGS2 (0.43) | MAPT | |
| SCHEMBL8690368 | 0.78 | GNRHR (0.43) | — | |
| SCHEMBL6982096 | 0.76 | MAPT (0.46) | MAPTALDH1A1KDM4EGAAMEN1 | |
| Hydrochloric Acid SCHEMBL8699219 | 0.75 | MAPT (0.45) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL8595591 | 0.74 | CTSV (0.46) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL6978088 | 0.71 | POLB (0.53) | POLB | |
| SCHEMBL8696015 | 0.71 | ALDH1A1 (0.42) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL6981037 | 0.70 | MAPT (0.49) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8698017 | 0.70 | CCNE1 (0.44) | MAPTALDH1A1KDM4EGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780437-A | ADMINISTERING TO TREAT SEX-HORMONE RELATED DISORDERS | MERCK & CO., INC. (US) | 1998-07-14 | — | — | US | disclosed |