Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 1.00 |
| ▸ | HTT | P42858 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.70 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.70 |
| ▸ | APP | P05067 | 1/20 | 0.64 |
| ▸ | SNCA | P37840 | 1/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | PARP1 | P09874 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CNR2 | P34972 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28542658 | 0.89 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL29377589 | 0.88 | ALDH1A1 (0.78) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL1418988 | 0.88 | ALDH1A1 (0.78) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL29503950 | 0.87 | ALDH1A1 (0.76) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL8758318 | 0.87 | ALDH1A1 (0.76) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL4363978 | 0.87 | ALDH1A1 (0.76) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL4363865 | 0.85 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL15471742 | 0.85 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL29071626 | 0.85 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL30487284 | 0.85 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2HTTLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9714240-B2 | Vinyl autotaxin inhibitor compounds | PHARMAKEA, INC. (US) | 2017-07-25 | — | — | US | disclosed |
| US-20160222000-A1 | VINYL AUTOTAXIN INHIBITOR COMPOUNDS | DF 2024 IP ACQUISITION, LLC | 2016-08-04 | — | — | US | disclosed |
| EP-3046905-A1 | VINYL AUTOTAXIN INHIBITOR COMPOUNDS | Pharmakea Inc. (US) | 2016-07-27 | — | — | EP | disclosed |
| CN-105130907-A | Pyrimidine compounds and use thereof | UNIV SHENYANG PHARMACEUTICAL | 2015-12-09 | — | — | CN | disclosed |
| WO-2015042053-A1 | VINYL AUTOTAXIN INHIBITOR COMPOUNDS | PHARMAKEA, INC. (US) | 2015-03-26 | — | — | WO | disclosed |
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160222000-A1 | VINYL AUTOTAXIN INHIBITOR COMPOUNDS | ENPP2, SERPINB1, SERPINB10 | ALDH1A1 4514/4885SMN1; SMN2 2623/4885HTT 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.