Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693647 | 0.88 | KMT2A (0.49) | KMT2AAKR1C3AKR1C1LMNAMCOLN3 | |
| SCHEMBL9093759 | 0.82 | ALDH1A1 (0.47) | AKR1C3AKR1C1HDAC3HDAC4HDAC1 | |
| SCHEMBL8694414 | 0.79 | AKR1C3 (0.42) | KMT2AAKR1C3AKR1C1HDAC3HDAC4 | |
| SCHEMBL9093848 | 0.76 | HCRTR1 (0.39) | KMT2AAKR1C3HDAC3HDAC4HDAC1 | |
| SCHEMBL8690346 | 0.76 | HTT (0.47) | KMT2ALMNAHTTALDH1A1GAA | |
| SCHEMBL8691819 | 0.76 | ALDH1A1 (0.39) | KMT2AAKR1C3AKR1C1HDAC3HDAC4 | |
| SCHEMBL9093847 | 0.74 | MCOLN3 (0.64) | KMT2AAKR1C3AKR1C1LMNAMCOLN3 | |
| SCHEMBL9093918 | 0.73 | AKR1C3 (0.44) | KMT2AAKR1C3AKR1C1LMNAMCOLN3 | |
| SCHEMBL9093869 | 0.73 | HTR6 (0.44) | KMT2AALDH1A1 | |
| SCHEMBL9093840 | 0.72 | KMT2A (0.37) | KMT2AAKR1C3AKR1C1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707985-A | Naphthyl-, quinolyl- and isoquinolyl- sulfonamide derivatives as cell adhesion modulators | TANABE SEIYAKU CO. LTD. (JP) | 1998-01-13 | — | — | US | claimed |
| WO-1996040641-A1 | SULFONAMIDE DERIVATIVES AS CELL ADHESION MODULATORS | TANABE SEIYAKU CO., LTD. (JP) | 1996-12-19 | — | — | WO | disclosed |