Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4474912 | 0.84 | KMT2A (0.45) | KMT2AMEN1TSHRPOLBALDH1A1 | |
| SCHEMBL10676915 | 0.81 | PDE4A (0.44) | KMT2AMEN1TSHRPOLBALDH1A1 | |
| SCHEMBL6078409 | 0.80 | ESRRA (0.42) | HTTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL31468113 | 0.80 | ESRRA (0.42) | HTTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL24955836 | 0.79 | HTT (0.60) | HTTKMT2AMEN1SLC22A6TSHR | |
| SCHEMBL6693971 | 0.76 | HTT (0.53) | HTTKMT2AMEN1SLC22A6TSHR | |
| SCHEMBL9035473 | 0.76 | HTT (0.57) | HTTKMT2AMEN1SLC22A6TSHR | |
| SCHEMBL27656394 | 0.76 | HTT (0.53) | HTTKMT2AMEN1SLC22A6TSHR | |
| SCHEMBL8690648 | 0.76 | KMT2A (0.47) | HTTKMT2AALDH1A1KDM4EGAA | |
| SCHEMBL9780447 | 0.76 | HTT (0.49) | HTTKMT2AMEN1SLC22A6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707985-A | Naphthyl-, quinolyl- and isoquinolyl- sulfonamide derivatives as cell adhesion modulators | TANABE SEIYAKU CO. LTD. (JP) | 1998-01-13 | — | — | US | disclosed |
| WO-1996040641-A1 | SULFONAMIDE DERIVATIVES AS CELL ADHESION MODULATORS | TANABE SEIYAKU CO., LTD. (JP) | 1996-12-19 | — | — | WO | disclosed |